| Objective Explore the imaging and clinical features of small cell lung cancer,and summarize the significance of SCLC imaging classification for the diagnosis of SCLC,and analyze its clinical research characteristics to help early diagnosis,differential diagnosis and individualized treatment of SCLC.Methods We collected the clinical information of patients diagnosed as SCLC at the General Hospital from January 2015 to January 2020,which including Imaging findings of chest enhancement CT,case characteristics,pathological data,tumor markersand therapeutic effects.Results There were 138 patients in this study,including 98 male patients(71.0%)and40 female patients(29%).88patients(63.8%)were younger than 65 years old.The clinical manifestations were cough in 68 cases(49.3%),hemoptysis in 35 cases(25.3%),shortness of breath in 76 cases(55.1%),chest pain in 23 cases(16.7%),hoarseness in 1 case(0.7%),neck mass in 23 cases(16.6%),weight loss in 27 cases(19.6%).Among them,82cases(59.4%)had a smoking index greater than 400.Duration of disease 1 week to 3 years and the average time to visit the doctor3.1months.In CT classification,50 cases were central mediastinal type,accounting for 36.2%;32cases of central hilum type(23.2%);Peripheral mediastinum type was found in 20 cases(14.6%);13cases of peripheral type(9.5%);2cases of pleural seeding type(1.4%);6cases of lymphatic disseminated type(4.3%);5cases of pneumonia-like type,accounting for 3.6%;10cases of lobule type(7.2%).Conclusion1.Small cell lung cancer has poor clinical specificity.It is often seen with respiratory symptoms,such as cough,sputum,chest tightness,and shortness of breath.2.In the distant metastasis of small cell lung cancer,liver metastasis is more common in women.3.In the CT classification of SCLC the common central combined mediastinal type,central hilar type,peripheral type and peripheral combined mediastinal type are common,and the lymphatic metastasis type,lobular type,pneumonia-like type and pleural disseminated type are rare.4.CT signs of small cell lung cancer have certain characteristics,hilar lung mass with multiple mediastinal lymph node enlargement is common,can invade the mediastinal structure to form "frozen mediastinum" and "frozen mediastinum".Distant metastasis may occur in early stage,but its diagnosis still needs to be combined with clinical and pathological.5.CT enhanced assessment of mediastinal vascular invasion is be beneficial to diagnosis and staging,combined with clinical manifestations and pathology to improve the understanding and diagnosis of small cell lung cancer,which has positive significance for prognostic evaluation. |