Correlation Study Of NLR,MPO And Blood Stasis Syndrome Of Stable Angina Pectori

Objective:Objective to provide an objective basis for enriching the theory of Blood Stasis Syndrome by studying the correlation between NLR,MPO and Blood Stasis Syndrome of CHD stable angina pectoris.Methods:The outpatients of the First Affiliated Hospital of Heilongjiang University of traditional Chinese medicine from January 2020 to January2021 were selected,including 30 healthy people and 120 CHD patients with stable angina pectoris.CHD was divided into 90 cases of the Blood Stasis Syndrome group,30 cases in non-Blood Stasis Syndrome group,and 90 cases were divided into heart blood stasis syndrome group,qi stagnation blood stasis syndrome group and Qi deficiency blood stasis syndrome group.The basic information and NEU,LYM,NLR,MPO values of each group were observed and recorded.SPSS21.0 was used to analyze the correlation between NLR,MPO and Blood Stasis Syndrome of CHD.Results:1.Compared with the healthy control group,the NEU,NLR and MPO values of non-Blood Stasis Syndrome group and the Blood Stasis Syndrome group were increased,the differences were statistically significant(all P<0.05),and the value of LYM was decreased,the differences were not statistically significant(all P>0.05).2.Compared with the non-Blood Stasis Syndrome group,the NEU,NLR and MPO values of the Blood Stasis Syndrome group were increased,and the differences were statistically significant(all P<0.05),LYM decreased,and the difference was not statistically significant(all P>0.05).3.NEU,NLR and MPO of the Blood Stasis Syndrome group were heart blood stasis syndrome group>qi stagnation and blood stasis syndrome group>Qi deficiency and blood stasis syndrome group,the differences were statistically significant(all P<0.05),lym was contrary to the above results,the differences were not statistically significant(all P>0.05).4.The results of correlation analysis showed that NLR,MPO were positively correlated with Blood Stasis Syndrome(rs>0,P<0.05;rs>0,P<0.05),and positively correlated with the subgroups of Blood Stasis Syndrome(R~2>0,P<0.05;R~2>0,P<0.05).5.The area under the ROC curve of NLR is 0.813,and the maximum diagnostic index is 0.622 when the sensitivity is 82.2%and the specificity is80.0%;the area under the ROC curve of MPO is 0.807,when the sensitivity is72.2%and the specificity is 90.0%,the diagnosis The maximum index is0.622.Conclusion:1.Compared with the healthy control group,patients with stable angina pectoris of coronary heart disease have a higher degree of inflammation.2.In patients with stable angina pectoris of coronary heart disease,the degree of inflammation in the blood stasis syndrome group was more severe than that in the non-blood stasis syndrome group.3.Inflammatory factors Neutrophil to Lymphocyte ratio and myeloperoxidase can promote the formation of blood stasis syndrome in patients with coronary heart disease,and are positively correlated with the blood stasis syndrome.