Research On The Prescription Rule Of Chinese Medicine Diet For Atopic Dermatitis Based On The Theory Of TCM

Objective:From the literature and data mining,this paper makes a systematic study on the prevention and treatment of atopic dermatitis with medicinal diet under the guidance of the theory of "treating non-disease" of traditional Chinese medicine.It provides new ideas and methods for clinical prevention and treatment of atopic dermatitis and makes due contribution to the further inheritance of medicinal diet.Methods:1.Literature analysisFrom the network database such as zhiwang,weipu,wanfang,"Chinese medical code",the relevant literature on the prevention and treatment of atopic dermatitis by TCM theory of "treating no disease" and the prevention and treatment of atopic dermatitis by TCM diet were retrieved.The prevention and treatment of atopic dermatitis with medicated diet was studied theoretically.2.Data analysisTCM inheritance auxiliary platform was used to collect the prescriptions of medicinal diet similar to the prescription of atopic dermatitis in the dictionary of Chinese medicinal diet and the complete catalogue of Chinese medical diet prescription.Results:1.Based on the analysis of TCM medicinal diet literature and atopic dermatitis literature,this paper summarizes the principle of preventing and treating atopic dermatitis based on the theory of "treating non-disease".2.Selection of 769 prescriptions for rheumatic skin atopic dermatitis and 1017 prescriptions for blood deficiency and wind-drying atopic dermatitis.3.The results of distribution type of medicated diet showed that 769 prescriptions of rheumatic skin type of medicated diet were mostly tea and congee,accounting for 64.1%.1017 head blood deficiency wind dry type medicated diet type with soup type,congee type in the majority,accounting for 34.2%.4.The results of raw material frequency show that the formula of rheumatic skin type medicated diet involves 399 ingredients,and the top 10 ingredients are:achylosum(170),fangfeng(153),duhuo(126),coix seed(112),liquor(106),cinnamon(103),dendrobium(95),ligusticum(89),lotus seed(79)and wujia skin(78).Blood deficient wind dry type medicaments meal square involves raw material of 413 taste in all,use frequency row top 10 is respectively: Chinese wolfberry(143),egg(135),rice(116),pork(102),white sugar(95),dry ginger(94),Chinese yam(84),yellow rice wine(83),chicken(81),angelica(76).5.The results of association rule analysis showed that the top 10 list of raw material combinations of rheumatic medicated diet were: achyranthes bidentata and fangfeng(99);Protection against wind and independence(85);Achyranthes achyranthes and longhorns(72);Dendrobium and fangfeng(71);Achyranthes bidentata and eucommia ulmoides(71);Fangfeng,cinnamon(70);Achyranthes root and cinnamon(69);Dendrobium and achyranthes bidentata(69);Fangfeng and coix seed(69);Fangfeng,lotus seed(64).The raw material combination of blood-deficient and wind-drying medicated diet is listed in the top 10: egg,ginger(66);Chinese wolfberry and cooked rehmannia(63);Angelica sinensis and cooked rehmannia glutinosa(62);Eggs and pork(60);Chinese wolfberry and angelica(54);Eggs,chicken(52);Chrysanthemum and Chinese wolfberry(50);Liquor,cooked rehmannia(50);Chinese wolfberry and ginger(48);Chrysanthemum,egg(45).6.Based on the entropy clustering algorithm of complex system,6 pairs of core combinations of raw materials were obtained.6 pairs of core combination of blood deficiency and wind dryness type medicinal food.7.Based on the unsupervised entropy hierarchical clustering algorithm,four pairs of core combinations of the new formula of rheumatic diet were obtained.4pairs of new combination of blood deficiency and wind dryness type medicinal diet.Conclutions:1.The regulation of rheumatism and skin medicated diet recipe is to strengthen spleen clearing damp,while the regulation of blood-deficient wind-dry medicated diet recipe is mainly to strengthen spleen and blood.Rheumatism accumulate skin type medicated diet recipe and blood deficient wind dry type medicated diet recipe commonly used raw material in japonica rice use frequency is resided high,rheumatism accumulate skin medicated diet recipe medium fangfeng and other raw material collocation use frequency is more,blood deficient wind dry medicated diet recipe medium medlar and other raw material collocation use frequency is more.2.It is suggested that tea,soup and soup should be the main recipes for preventing atopic dermatitis.Atopic dermatitis is a chronic,recurrent and pruritus skin disease,which is more common in infants and children.Traditional Chinese medicine oral taste is not good,the medical treatment of patients is poor,the medicinal diet has the characteristics of delicious,easy to eat,can improve the medical treatment of patients.3.Core combination of medicinal diet recipe for atopic dermatitis prevention and treatment under the guidance of the theory of "Treating diseases without disease" of Traditional Chinese medicine.(1)Prevention before disease-adjust body diet: rheumatism type atopic dermatitis prevention before disease recommended Yiweigu surface prescription core combination for pork belly,astragalus,japonica rice;Blood-deficient wind-dry atopic dermatitis should be cured before the disease.The core combination of the recommended medicine diet for tonifying deficiency is Ligusticum chuanxiong,cooked rehmannia,Angelica angelica,pork kidney,etc.(2)prevention of both diseases--treatment based on syndrome differentiation: the core combination of heat-clearing clearing damp medicinal diet is dendrobium,wind-proof,coix seed,lotus seed,Chinese yam,poria coia,coriander and ephedra.Blood deficiency,wind dryness,atopic dermatitis and disease prevention recommended medicine blood-nourishing and nourishing medicinal diet recipe core combination is tangerine peel,medlar,pork kidney.(3)Chai defence after-guprotect spleen and stomach: rheumatism aggregates type skin atopic dermatitis Chai defence after phase recommended spleen clearing damp core portfolio of medicinal food fang for watermelon green clothes,eel,celery,poria cocos,yam,lotus seed,etc.;Blood deficiency type wind dry atopic dermatitis Chai defence after phase recommended spleen nourishing blood medicinal food fang core portfolio as SSP,japonica rice,pork loin,mulberry,dwarf lilyturf,etc.