| Objective:The general data,imaging features,tumor markers,histopathological features,intraoperative conditions,clinical stages and postoperative recurrence of patients with borderline ovarian tumors(BOT)were retrospectively analyzed in order to improve the diagnostic accuracy of BOT and explore the related factors affecting the recurrence of BOT.Methods:The clinical data of BOT confirmed by pathology after operation in the first Hospital of Jilin University from January 2012 to August 2020 were analyzed retrospectively.It mainly includes:(1)the main clinical features before operation: name,chief complaint,age,height,weight,main symptoms,personal history,marriage and childbearing history,family history,common gynecological diseases and auxiliary examination results.(2)Intraoperative conditions: intraoperative findings(tumor size,location of tumor involvement,ascites,etc.)and rapid pathological results during operation.(3)postoperative treatment and follow-up results: mainly including postoperative pathology,adjuvant therapy and follow-up.SPSS25.0software was used to analyze the preoperative,intraoperative,postoperative and follow-up results.Results:(1)The average age of first onset was 43.78 ±15.56 years old.The average age of serous type patients was 42.46 ±13.66 years old,and that of mucous type patients was 43.52±17.65 years old.There was no significant difference between the two groups.There was significant difference between age and recurrence(P < 0.05).(2)There was significant difference in the positive rate of tumor markers between serous type and mucous type,such as serum CA125(P=0.001),CA199(P=0.040),CEA(P<0.001)and CA724(P=0.016).There was no significant difference in serum AFP(P=0.520)and HE4(P=0.488).There was no significant difference between the positive rate of the above tumor markers and recurrence(P> 0.05).(3)Color ultrasound showed that the cyst was multilocular and the positive rate was51.94%(187/360).There was significant difference between serous type and mucous type(P< 0.001).There was no significant difference between the positive rate of multilocular cyst and recurrence(P> 0.05).(4)Color ultrasound showed that the positive rate of fluid thickening in the cyst was67.05%(177/264).There was significant difference between serous type and mucous type(P=0.018).There was no significant difference between the positive rate of fluid thickening in cysts and recurrence(P > 0.05).(5)Color ultrasound revealed cystic tumors in 118 cases(32.78%),papillary structures or local solid areas in 94 cases(26.11%),dense hyperechoic spots in 25 cases(6.94%),and multiple echoes in the inner wall of the capsule in 123 cases(34.17%).There was significant difference between serous type and mucous type(P< 0.001).There was no significant difference between tumor nature and recurrence described by color ultrasound(P> 0.05).(6)There was significant difference between the involved side and the extent of borderline lesion and recurrence(P< 0.05),but there was no significant difference between the mode of operation,the type of lesion and recurrence(P > 0.05).(7)The average maximum diameter of tumor was 11.49 ±7.08 cm.The average maximum diameter of serous type was 8.13 ±4.42 cm,and that of mucinous type was 14.39±7.80 cm.There was significant difference between the two groups(P< 0.001).There was no significant difference between the maximum diameter of tumor and recurrence(P > 0.05).(8)There were 54 cases(16.02%)with peritoneal implantation and 283 cases(83.97%)without peritoneal implantation.There were 127 cases(35.47%)with ascites and 221 cases(61.73%)without ascites.There was no significant difference between ascites,peritoneal implantation and recurrence(P > 0.05).(9)182 patients(50.56%)underwent full staging surgery and 178 patients(49.44%)underwent fertility preserving surgery.There were 325 patients in stage I(90.27%),15 patients in stage II(4.17%),20 patients in stage III(5.56%),and no patients in stage IV.Among them,24 cases(6.7%)received postoperative chemotherapy and 336 cases(93.3%)did not receive chemotherapy.There was significant difference between operation scope,stage and recurrence(P<0.05),but there was no significant difference between chemotherapy and recurrence(P> 0.05).Conclusion:(1)The first onset of BOT is mostly in women of childbearing age.(2)The positive rate of serum CA125 was 53.11%.It can only be used as a reference for preliminary preoperative evaluation and monitoring of recurrence and progression of the disease,and the diagnosis still depends on the postoperative pathological results.(3)The positive rate of serum CA125 in serous type was higher than that in mucous type.The positive rates of serum CA199,CEA and CA724 in patients with mucous type were higher than those in patients with serous type.(4)Color ultrasound showed that the multilocular positive rate of BOT was 51.94%,and the positive rate of fluid thickening in the capsule was 49.17%,which can provide reference for the preoperative diagnosis of BOT.(5)Color Doppler ultrasound showed that the positive rate of polylocular cyst and the positive rate of fluid thickening in the cyst of mucous type were higher than those of serous type.(6)Color ultrasound showed that there were nipples or local solid areas in the capsule and the incidence of strong echo in the capsule was 67.22%.When color ultrasound revealed the above imaging features,attention should be paid to the diagnosis of BOT.(7)The tumor size of patients with mucinous type was larger than that of patients with serous type.(8)Serous BOT involves more bilateral ovaries than mucus BOT.(9)The accuracy of rapid pathological diagnosis of BOT during operation was 91.14%.Rapid pathological examination provides an important reference for making a correct operation plan.(10)Late FIGO stage,bilateral ovary involvement and fertility preserving surgery were risk factors for postoperative recurrence,and it was still a borderline tumor at the time of recurrence. 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