The TCM Syndromes Of Patients With An Acute Attack Of Asthma Are Correlated With The Relevant Inflammatory Indicators

Objecti veTo explore the correlation between TCM syndromes and related inflammatory indicators of patients with an acute attack of asthma,find the rules and characteristics between them,and better assist the diagnosis and treatment of TCM syndromes of asthma in clinical work.MethodsThis project collected relevant inflammatory indicators(neutrophil,eosinophil,neutrophil-lymphocyte ratio,platelet-lymphocyteatio,C-reactive protein,procalcitonin),and a statistical processing was conducted to explore the correlation between various TCM syndromes and inflammatory indicators.ResultsThere are a total of 104 patients.As for gender,the number of female patients is larger than that of male patients.In terms of age,their average age is 63.49 years.As for the seasons,this disease is more likely to happen in spring.In terms of the incentives,weather changes are more common.In terms of tongue quality,the dark red tongue is the most common in the group with exogenous cold and internal fluid-retention syndrome;the red tongue is the most common in the group with phlegm-heat obstructing lung syndrome;the light red tongue is the most common in the group with wind-phlegm-obstructing lung syndrome;the light red tongue is the most common in the group with phlegm-turbidity obstructing lung syndrome.As for the coated tongue,the thin and yellow tongue is the most common in the group with exogenous cold and internal fluid-retention syndrome;the yellow greasy tongue and thin yellow tongue are the most common in the group with phlegm-heat obstructing lung syndrome;the thin white tongue and thin yellow tongue are the most common in the group with wind-phlegm-obstructing lung syndrome;the thin yellow tongue and thin white tongue are the most common in the group with phlegm-turbidity obstructing lung syndrome.As for the pulse condition,the floating tight pulse and chord slippage pulse are more common in the group with exogenous cold and internal fluid-retention syndrome;the slippage rapid pulse and chord slippage pulse are the most common in the group with phlegm-heat obstructing lung group;the chord slippage pulse is the most common in the group with wind-phlegm-obstructing lung;the chord slippage pulse is more common in the group with phlegm-turbidity obstructing lung.In terms of the differences in inflammation indicators among various TCM syndromes,the neutrophils level among all syndrome groups is the highest in the group with phlegm-heat obstructing lung,followed by exogenous cold and internal fluid-retention syndrome,wind-phlegm obstructing lung syndrome,and phlegm-turbid obstructing lung syndrome,among which the ratio of neutrophile granulocyte and lymphocyte of phlegm-heat obstructing lung syndrome is relatively high compared with other syndromes(P＜0.05).The ratio of neutrophils and lymphocytes of phlegm-heat obstructing lung syndrome is relatively high compared with other syndromes(P＜0.05).There is no statistical significance in PLR values among various syndromes(P＞0.05).The level of eosinophilic granulocyte of the wind-phlegm-obstructing lung syndrome is the highest among all syndrome groups,followed by the phlegm-turbidity obstructing lung syndrome,the phlegm-heat obstructing lung syndrome,and exogenous cold and internal fluid-retention syndrome.The level of eosinophilic granulocyte of the wind-phlegm obstructing lung syndrome is higher than that of other syndromes(P＜0.05).The C-reactive protein levels of each syndrome group from the highest to the lowest are as follows:phlegm-heat obstructing lung syndrome,exogenous cold and internal fluid-retention syndrome,wind-phlegm obstructing lung syndrome,and phlegm-turbidity obstructing lung syndrome.The C-reactive protein level of phlegm-heat obstructing lung syndrome is relatively higher than that of other syndromes(P＜0.05);The levels of procalcitonin in each syndrome group from the highest to the lowest are as follows:phlegm-turbidity obstructing lung syndrome,exogenous cold and internal fluid-retention syndrome,wind-phlegm obstructing lung syndrome,and phlegm-heat obstructing lung syndrome;The level of procalcitonin in each group is not statistically significant(P＞0.05).The C-reactive protein level is positively correlated with phlegm-heat obstructing lung syndrome(P＜0.05),that is,the higher the C-reactive protein level is,the more likely the patients are to have the phlegm-heat obstructing lung syndrome;Lymphocyte count and platelet-lymphocyte ratio are positively correlated with sputum-turbid obstructing lung syndrome(P＜0.05),that is,patients are more likely to have sputum-turbid obstructing lung syndrome when LYM and PLR increase.ConclusionThe TCM syndromes of patients with an acute attack of asthma are correlated with the relevant inflammatory indicators,such as neutrophil count,eosinophil count,lymphocyte count,C-reactive protein,neutrophil-lymphocyte ratio,and platelet-lymphocyte ratio,which can provide a certain reference for the clinical syndrome differentiation of acute attack of asthma.