Research Progress In Correlation Between Vitamin D And Sarcopenia In The Elderly

With the acceleration of the aging of the society,the prevalence of sarcopenia in the elderly population is increasing,which is likely to lead to falls,fractures and loss of independent living ability in the elderly,seriously affecting the quality of life of the elderly,and increasingly becoming a global health problem.Current less about muscle disease pathogenesis research mainly involves the decomposition of skeletal muscle protein synthesis imbalances and mitochondrial dysfunction,oxidative stress,inflammatory factors disorder and insulin resistance,etc.,vitamin D may by preventing oxidative stress damage and protection of mitochondrial function to reduce muscle strength,lower quality,maintain skeletal muscle function.Vitamin D deficiency is closely related to the occurrence and development of sarcopenia.At present,the specific mechanism of the effect of vitamin D on sarcopenia needs further research.There is no consensus on a strategy for vitamin D supplementation to prevent and treat sarcopenia.