Research On A New Microstructure Radiation Dosimeter Based On Electrospinning And Microfluidic Technology

Nuclear technology has become more and more widely used in many fields such as industry,agriculture,medicine,etc.In these applications,accurate and convenient radiation dose measurement is a guarantee of application effect and quality.For example,when radiation disinfecting medical supplies,the dose is generally measured with a thin film dosimeter to ensure the sterilization effect.However,the traditional thin film dosimeter is expensive to prepare,has a long cycle,the prepared discolored film has poor uniformity,and the presence of air bubbles,which seriously affects the application of the thin film dosimeter.Another major application of nuclear technology in medicine is radiation therapy.Due to the special nature of treatment,accurate dose verification needs to be performed before radiotherapy.Generally,traditional one-dimensional dosimeters can only measure the dose distribution of discrete points and radiation discoloration dose tablets.A two-dimensional dose distribution can be measured.The commonly used Fricker dosimeter can meet the three-dimensional dose verification,but due to the inevitable diffusion of Fe³⁺in the dosimeter after irradiation,this also leads to blurred radiation dose at the edge,resulting in spatial resolution.reduce.Aiming at the problems existing in the application of radiation-sensitive materials and radiation dosimeters,this article has carried out research on the preparation and performance of radiation-sensitive micro-nano materials.The main contents of the research are as follows:1.Electrospinning technology was used to prepare new-type irradiated discolored micro-nano films,and the effects of different conditions on film morphology and film formation quality were investigated.Under different doses of radiation,observe the color change of the film,study the mechanism of the film’s radiation discoloration,and obtain its radiation response law.By using the prepared radiochromic micro-nano film,a reversible alarm for medical site radiation monitoring and a color-changing film dosimeter for medical device irradiation are constructed,which solves the problems of long traditional film preparation cycles,poor uniformity,and air bubbles.2.We built a device for preparing micro-nano gel beads using dual microfluidic channels,and prepared Fricke gel beads wrapped with polydimethylsiloxane（PDMS）.The core-shell structure has uniform size.Good optical transparency and excellent mechanical properties,while maintaining good radiation dose response characteristics.The PDMS shell limits the ion diffusion to the small balls,which solves the problem of spatial dose ambiguity caused by iron ion diffusion in traditional gel dosimeters.3.We packed the prepared Fricke gel pellets into a reduced-size stomach model,simulated the phantom,and studied the mechanical stability of the pellets when stacked in the phantom.Using the finite element method to simulate the spatial distribution of several absorbed doses in the phantom,the diffusion behavior of iron ions corrects the dose blur caused by the diffusion in the sphere to obtain an accurate spatial dose distribution.The theoretical basis is provided in the dose verification of IMRT.