| Hepatitis C virus (HCV) is an emerging global public health issue with particular relevance in multiply transfused renal dialysis patients. This investigation determined the prevalence and risk factors for HCV infection in the Northern Alberta Renal Program (NARP). Ninety-two percent of eligible patients (n = 336) provided informed consent to participate. Participants were interviewed to gather risk factor information, and using multiple logistic regression analysis, a predictive model for HCV infection in the NARP was illustrated. Ill-defined modes for propagating blood-borne pathogens have been described and evidence against nosocomial transmission of HCV is provided. Self-reported patient transfusion histories were also validated against documented records. It emphasized the need to communicate clearly medical interventions in chronically ill patients and the responsibility to utilize all available information sources for exposure histories. Communicating about risk of infectious diseases must be reasoned and based on the best available epidemiological evidence. |
