| Although the prevalence of benign prostatic hyperplasia (BPH) is very high among older men, little is known about the causes of BPH. The objectives of this study are to explore the relationship between dietary factors, physical activity in teen years and BPH. The data for this thesis come from a prostate cancer case-control study that was conducted in Kingston Ontario during 1997–1999. Cases consist of 95 incident BPH cases, diagnosed by transrectal ultrasound or through transurethral prostatectomy within one year prior to enrollment, and without evidence of prostate cancer. Subjects investigated in the same urology clinic and without clinical evidence of prostate disease are controls (n = 271). Dietary intake two years prior to enrollment was assessed by a food frequency questionnaire, and blood samples were donated for measurement of plasma concentrations of vitamins A and E and lipid fractions.; Our results indicate that there is an increased risk of BPH associated with nonalcoholic drinking, especially with soft drinks, while the mechanisms are unknown. Total cholesterol in blood sample is positively associated with BPH risk. (Abstract shortened by UMI.)... |
