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The effect of dietary hempseed on atherosclerotic plaque formation and contractile function of the aorta from hypercholesterolemic rabbits

Posted on:2006-03-23Degree:M.ScType:Thesis
University:University of Manitoba (Canada)Candidate:Gavel, Nicole TFull Text:PDF
GTID:2454390005997733Subject:Biology
Abstract/Summary:
Atherosclerosis is a chronic disease which has important health implications. A number of risk factors for atherosclerosis have been identified including a poor diet that is high in saturated fats and cholesterol. Omega-3 polyunsaturated fatty acids from fish oil and flaxseed have been studied for their beneficial cardiovascular effects. These include effects on atherogenesis, platelet aggregation and adhesion, and improving vascular tone following atherogenesis. Research has shown that the ratio of omega-6 to omega-3 fatty acids is important in modulating subsequent eicosanoid metabolism and the physiological effects mediated by the metabolites. Hempseed has the optimal ratio of 4:1 omega-6 to omega-3 fatty acids, which makes this plant an ideal nutraceutical with cardioprotective effects.; This study examined the effects of various dietary interventions on vascular function of male New Zealand white rabbits. (Abstract shortened by UMI.)...
Keywords/Search Tags:Effects
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