An Evaluation Study On The Efficacy Of Taijiquan Combined With Qigu Capsules In Preventing And Treating The Elderly With Liver And Kidney Insufficiency Syndrome

Objective:Dysmobility syndrome?DS?is the most common chronic degenerative tendon and bone disease in the elderly.In the report of the World Health Organization?WHO?participating in the Global Aging and Adult Health Research?SAGE?,it was clearly pointed out that the increased risk of falls and fractures is a major problem affecting the active health of the elderly worldwide and a powerful indicator for predicting the future life expectancy of the elderly.Therefore,it is of great and positive social significance to solve the problem of disturbance of physical activity,delay the decline of musculoskeletal system and improve the motor function of the elderly.This study hopes to carry out the clinical study of Taijiquan combined with Qigu Capsule to improve the activity Dysmobility syndrome of the elderly,in order to find an effective,simple and safe intervention program,improve the quality of life of the elderly,and ultimately prolong their life.Method:In this study,we used randomized controlled principles to select 101 patients who met the inclusion criteria for liver-kidney deficiency dysfunction syndrome in three communities.They were randomly divided into control group?33 cases?,exercise group?34 cases of Taijiquan?and combined treatment group?34 cases of Taijiquan combined with Qigu capsule?.The control group did not intervene to record the patient's daily diet,lifestyle,etc.;the exercise group guided the Taijiquan exercise;the combined treatment group was given the joint intervention of Taijiquan and Qigu capsule.The observation time of the three groups was 24 weeks.The TCM syndrome scores,VAS scores,fall risk assessment,bone mineral density and biochemical parameters of the three groups before,12 and 24 weeks were compared to evaluate the clinical efficacy.At the same time,before and after the intervention.Changes in safety indicators such as blood routine,urine routine,liver and kidney function.All data were analyzed by statistical analysis software SPSS21.0,and P<0.05 was considered statistically significant.Results:?1?The scores of TCM symptoms in the combined treatment group,the exercise group and the blank control group decreased after 12 weeks and 24 weeks of treatment.After 12 weeks of treatment,the combined treatment group was better than the exercise group and the blank control group,and the exercise group was also better than the blank control group.After 24 weeks of treatment,the clinical effects of the combined treatment group,the exercise group and the blank control group were better than the blank control group,while the combined treatment group was better than the blank control group.The effect of treatment group was more obvious?P=0.006<0.05?.?2?Visual analogue pain score?VAS?of the three groups showed that the pain score of the three groups decreased after 12 weeks and 24 weeks of treatment.After 12weeks of treatment,the combined treatment group,exercise group and blank control group had better curative effect than blank control group.After 24 weeks of treatment,the clinical effect of the combined treatment group,exercise group and blank control group was better than blank control group,while the clinical effect of the combined treatment group was better than that of the blank control group.The pain relief effect of the combined treatment group was more significant?P=0.000<0.05?.?3?After 24 weeks of treatment,the fall scores of the combined group and the exercise group were significantly different from those before treatment?P=0.000<0.05?.There was no significant difference between the blank control group and the control group?P=0.224>0.05?.After 24 weeks of treatment,there was a significant difference in the fall risk score between the combined group and the exercise group?P=0.004<0.05?,which was reduced to a low-risk segment;after 24 weeks of treatment,there was a significant difference in the fall score between the combined group and the blank control group?P=0.000<0.05?;after 24 weeks of treatment,there was a significant difference between the exercise group and the blank control group?P=0.000<0.05?.?4?The BMD values of lumbar vertebrae(L_1-4)and femoral neck in the combined treatment group and the exercise group increased after 24 weeks of treatment.Compared with the blank control group,the clinical effect of the combined treatment group,the exercise group was better than that of the blank control group,and the combined treatment group was more significant.There was no significant difference in total hip bone mineral density after 24 weeks treatment compared with before treatment.It indicated that Taijiquan combined with Qigu capsule could improve the BMD status of patients with dyskinesia syndrome for a long time,but compared with the other two groups,the combined treatment group could better improve the BMD and increase the bone strength of patients.?5?Serum calcium,phosphorus,alkaline phosphatase and beta-collagen did not improve significantly after 12 and 24 weeks of treatment in the three groups,and the curative effect was not obvious.Parathyroid hormone,osteocalcin and vitamin D in the combined treatment group and exercise group had certain effects after 12 and 24 weeks of treatment.Compared with the exercise group and the blank control group,the three bone metabolism indexes in the combined treatment group improved significantly.However,in general,the treatment of ADS needs a long time to improve the biochemical indicators of bone metabolism.?6?Before treatment,there was no significant difference in basic vital signs?body temperature,heart rate,respiration,blood pressure?between the three groups?P>0.05?.The blood routine,urine routine,liver and kidney function,liver and kidney function?ALT,AST,total bilirubin,albumin,urea nitrogen,creatinine,uric acid?of the three groups before and after treatment were analyzed and observed.There was no necessary link between the clinical trial and no abnormality of the above indicators and any adverse events occurred during the follow-up of the trial.Conclusion:Taijiquan exercise alone,or Taijiquan combined with Qiong Capsule has a good clinical effect in the prevention and treatment of Dysmobility syndrome in the elderly.It is characterized by improved back pain,waist and knee weakness,lower limb cramps,difficulty walking,and inability to Heavier clinical symptoms;to a certain extent,it can reduce the risk of falls in the community,effectively increase bone density,and regulate bone metabolism.