| ObjectiveTo observe the pathogenesis of secondary lymphedema of erysipelas in the lower extremities through the collection of clinical data of such patients.A randomized controlled study was conducted to evaluate the efficacy and safety indicators of micro-acupuncture therapy on efficacy and safety indicators through the observation of symptoms,signs and auxiliary imaging performances of secondary erysipelas secondary lymphatic edema,and discuss its mechanism.To explore the intervention effect of this therapy on secondary lymphedema infection,establish the standard operational procedure of this therapy,and provide a preliminary basis for clinical promotion.MethodsA total of 50 patients with secondary lymphedema of erysipelas in the lower extremities were randomly divided into a treatment group and a control group with 25 cases each.The control group was orally administered with diosimine tablets 0.9 g twice daily,while the treatment group was administered with additional micro-acupuncture on the basis of the control group.Both groups were treated once a week for a period of 8 weeks.Before and after treatment,the patients' circumference,calculation of reduction degree,Doppler ultrasound of subcutaneous soft,pain score,duration of depression edema and syndrome score statistics were recorded.The safety indicators were also assessed before and after treatment.Comprehensive evaluation of clinical efficacy was made based on the improvement in syndromes and changes in indicators.Result1 Characteristics of di sease onsetThrough analyzing the 50 patients included in this study,we noticed that the ages of the patients were concentrated in the age group of 56-60 years old.Before the onset of the disease,the frequency of erysipelas on the affected limb was concentrated at 3 times.The Miller stage of lymphedema was concentrated at Stage 2.The most swollen parts of the affected limb were mostly at the upper ankle level.2 Sum of circumferences and degree of reduction and reduction of affected limbsCompared with the time of enrollment,after 8 weeks of treatment,the total circumference of the measurement point of the affected limb of the treatment group and the control group were significantly reduced(P<0.05),which were reduced by 8.504±0.309cm and 2.624±0.07cm respectively.The comparison between the two groups was statistically significant(P<0.05).Compared to the control group,the reduction and reduction of the affected limbs in the treatment group were significantly increased after the treatment,and the comparison between the groups was statistically significant(P<0.05).The treatment group was superior to the control group in reducing the circumference of the affected limb and increasing the reduction and reduction of the limb.3 Degree of thickness of the subcutaneous tissueCompared to the time of enrollment,after 8 weeks of treatment,the thickness of the subcutaneous soft tissue at both measurement points at the middle and lower legs of the two groups of patients was reduced.The treatment group decreased by 0.456±0.149 and 0.500±0.147 respectively.The control group decreased by 0.250±0.075 and 0.362±0.091 respectively.The intragroup comparison(P<0.05)and the intergroup comparison(P<0.05)showed that the thickness of the subcutaneous soft tissue of the affected limbs in both groups improved significantly,and the treatment group was significantly superior to the control group.4 VAS pain scoreAfter 8 weeks of treatment,the VAS pain score of the treatment group decreased by 1.760±0.233,while the control group decreased by 0.080±0.100.The comparison between the treatment groups was statistically significant(P<0.05),and the control group was not statistically significant(P>0.05).Comparison between the groups was statistically significant(P<0.05).The treatment group experienced significant improvements in pain symptoms,while the control group did not experience significant improvement in terms of pain,and the treatment group is superior to the control group.5 Duration of pitting edemaAfter 8 weeks of treatment,the duration of pitting edema in the affected limbs of both groups was significantly reduced,and the reduction in the control group and treatment group was 13.28±1.041 seconds and 7.62±0.237 seconds respectively.The P-value obtained from intragroup comparison was<0.05,and the P-value obtained from intergroup comparison in the group was P<0.05,all of which were statistically significant.There was an improvemen t in the duration of pitting edema in both groups,and the treatment group was superior to the control group.6 Comparison of efficacyBased on the changes in syndrome scores before and after treatment,the treatment group had 0 cases of complete recovery,4 markedly effective cases,19 effective cases,2 ineffective cases,and the total effective rate was 92%.In the control group,there were 0 cases of complete recovery,0 markedly effective cases,19 effective cases,and 6 ineffective cases,and the total effective rate was 76%,Comparison between both groups was P<0.05.Based on the changes in the total reduction and reduction of the circumference of the measurement site of the affected limb,0 cases of complete recovery,5 markedly effective cases,19 effective cases,1 ineffective cases,and the total effective rate was 96%.In the control group,there were 0 markedly effective cases,18 effective cases,and 7 ineffective cases.The total effective rate was 72%.Comparison between both groups was P<0.05.The calculation methods based on two different efficacy indexes show that the difference in the effective index between the two groups of patients after treatment is statistically significant(both P values were less than 0.05),proving that the treatment group was better than control group after 8 weeks of treatment.7 Comparison of recurrence ratesFollow-up was continued for 3 months after treatment,and 2 cases of relapse were discovered in the treatment group with a recurrence rate of 8%,while there were 8 cases of relapse in the control group with a recurrence rate of 32%,Based on the results of this study,the recurrence rate in the treatment group was lower than that of the control group after treatment was discontinued for 3 months.ConclusionSecondary lymphedema of erysipelas in the lower extremities is more common in the upper ankle region,and its clinical symptoms are less severe than that of tumor-associated secondary lymphedema.Microneedle acupuncture has a definitive curative effect and it can effectively relieve the degree of limb swelling,reduce the thickness of subcutaneous soft tissue,relieve pain symptoms and reduce the duration of pitting edema in patients with lower infection-associated secondary lymphedema in the lower extremities.The therapeutic effects are significantly superior to the control group with sole administration of diosmin,with good long-term efficacy and low recurrence rates. |
PDF Full Text Request