The Clinical Study Of Qianlietai Tablet, Tamsulosin Combined With Chinese Medicine Sitz Bath In The Treatment Of Type ?b Prostatitis (damp-heat Stagnation Syndrome)

Objective:To study and discuss the clinical effect of Qianlietai tablet and tamsulosin combined with traditional Chinese medicine sitting bath treating prostatitis?b:syndrome of damp heat stasis;to explore the clinical efficacy and safety of this treatment regimen,which provides a new idea for clinical application of integrated traditional Chinese medicine and modern medicine.Methods:A total of 60 patients with type ?b chronic prostatitis(damp heat stasis syndrome)who met the inclusion criteria from April 2019 to September 2019 in the urologic surgery clinic were selected and divided into a therapeutic group and a control group,with 30 patients in each group.The treatment of the therapeutic group was oral Qianlietai sheet,2.2g,Tid,and tamsulosin,0.2mg,Qn,combined with traditional Chinese medicine sitting bath for 6 weeks.The control group of patients was treated with oral Qianlietai sheet,2.2g,Tid,combined with tamsulosin,0.2mg,Qn,for 6 weeks.Basic data(age,course of disease,severity of illness etc.),and NIH—CPSI,TCM syndrome scores,lecithin body count before and after intervention treatment of two groups of patients were collected and statistically analyzed.In the course of therapia,the adverse reactions had been monitored closely and dealt with reasonably timely,to summarize and evaluate the efficacy and security of two groups of treatment measures.3 months after the end of the clinical treatment stage,a follow-up visit will be conducted,and recurrence rate between the two groups was analyzed and contrasted.Results:1.Comparison of clinical results:In the control group,one patient fell off and 29 patients actually received the test,0 clinic control,6 cases significantly effcctive,14 cases effective and 9 cases ineffective,overall response rate was(20/29)68.97%;in the therapeutic group,there were 30 patients,4 clinic control,16 significantly effective,8 effective and 2 ineffective,total effective was(28/30)93.00%.The therapeutic effect of the treatment group was obvious,which had significant difference in the total effective rate between the two groups,by chi-square test,P<0.05.2.Evaluation of clinical indicators of western medicine:The pain degree,micturition symptom,quality of life and total score of NIH-CPSI in the two groups were significantly lower than those before treatment(P<0.05),after therapeutic intervention,the indicators of NIH-CPSI of the therapeutic group was notably better than the control group(P<0.05).After treatment,the number of lecithin corpuscles in the two groups both increased,and the increase in the therapeutic group was significantly higher than that in control group(P<0.05).3.Evaluation of clinical indicators of TCM:There was no statistical difference in the total scores of TCM syndrome differentiation between the two groups before the experimental intervention.After the clinical treatment,the total scores of the two groups decreased,and the scores of the therapeutic group were prominently lower than that of the control group(P<0.05).4.Security assessment:One patient in the control group was excluded due to business trip abroad,all other patients completed the treatment according to the trial plan.During the treatment,the basic vital signs of the two groups were normal,and there were no obvious adverse reactions in gastrointestinal tract,nervous system,urinary system,skin,etc.5.Relapse rate:3 months after the end of the clinical treatment stage,a follow-up visit will be conducted to the clinical effective members.The recurrence rate was(1/28)3.57%in the therapeutic group and(3/20)15.00%in the control group.The therapeutic group was significantly lower than the control group.Conclusion:Qianlietai tablet,tamsulosin combined with traditional Chinese medicine sitting bath,which can significantly reduce the NIH-CPSI scores and the total scores of TCM syndrome and substantially increase the number of EPS lecithin corpuscles,has outstanding clinical effect on patients with type ?b prostatitis(damp-heat stasis syndrome)and can effectively improve the quality of life of patients,with many advantages of high safety and low recurrence rate,etc.