Analysis Of The Distribution Of TCM Syndrome Types Of Primary Lung Cancer And Its Related Factors

Purpose: To study the distribution of TCM syndrome types in primary lung cancer and further analyze the related factors affecting TCM syndrome differentiation and classification,so as to provide reference for clinicians in TCM syndrome type judgment.Material and method: This subject uses retrospective investigation and research method to collect the clinical data of 214 patients with primary lung cancer,design the clinical questionnaire of lung cancer,use the medical record system of the affiliated hospital of Liaoning University of traditional Chinese Medicine to retrieve the primary lung cancer patients who first came to our hospital from October 2017 to March 2020,and fill in the clinical questionnaire of lung cancer in turn.The distribution of TCM syndromes in patients with primary lung cancer was summarized,and the related factors affecting TCM syndromes distribution were analyzed by statistical software.Results:1.primary lung cancer patients with TCM syndrome type distribution of qi-yin deficiency type,followed by qi stagnation blood stasis type,phlegm dampness accumulation lung type,water drink internal stop type.Namely lung cancer patient TCM syndrome type distribution: Qi Yin two deficiency type > Qi stagnation blood stasis type > phlegm dampness accumulation lung type > water drink internal stop type.analysis showed that the distribution of TCM syndromes was statistically significant(P<0.05).2.By statistical analysis,there was no statistical significance in the distribution of TCM syndromes in different age groups(P>0.05).3.By statistical analysis,there was no statistical significance in the distribution of TCM syndrome type(P>0.05).4.Qi stagnation and blood stasis are the most common TCM syndromes in patients with stage I,followed by deficiency of both qi and yin,retention of phlegm and dampness in the lung,and internal retention of water.Qi stagnation and blood stasis are common in Phase II,followed by deficiency of both Qi and Yin,retention of phlegm and dampness in lung,and internal retention of water.Phase III is mainly characterized by deficiency of both qi and yin and spleen deficiency and phlegm-dampness syndrome,followed by qi stagnation and blood stasis syndrome and internal retention of water.The deficiency of both qi and yin is the most common in phase IV,followed by qi stagnation and blood stasis,internal retention of water and phlegm-dampness in lung.After analysis,the distribution of different TNM stages in TCM syndromes has statistical significance(P<0.05).5.The TCM syndromes of patients with hydrothorax are mainly qi stagnation and blood stasis and internal retention of water,followed by deficiency of both qi and yin and retention of phlegm-dampness in lung.Deficiency of both qi and yin is the most common type of patients without hydrothorax,followed by qi stagnation and blood stasis,phlegm-dampness accumulation in lung,and internal retention of water.After analysis,the distribution of hydrothorax in TCM syndromes has statistical significance(P<0.05).6.the distribution characteristics of TCM syndrome types of metastatic patients are:deficiency of both qi and yin >qi stagnation and blood stasis >phlegm-dampness accumulation in lung >internal retention of water;The distribution characteristics of TCM syndromes of non-metastatic patients are as follows: qi stagnation and blood stasis syndrome >deficiency of both qi and yin syndrome >phlegm-dampness accumulation in lung syndrome >internal retention of water;After analysis,the presence or absence of metastasis is statistically significant in the distribution of TCM syndromes(P<0.05).7.Qi stagnation and blood stasis syndrome with Karnofsky score above 70 is the most common,followed by deficiency of both qi and yin,retention of phlegm and dampness in lung,and internal retention of water.Deficiency of both qi and yin with a score of 40-70 is the most common,followed by qi stagnation and blood stasis,phlegm-dampness accumulation in lung,and internal retention of water.The deficiency of both qi and yin with Karnofsky score below 40 is the most common,followed by qi stagnation and blood stasis,retention of phlegm and dampness in lung,and internal retention of water.The analysis shows that the Karnofsky score of different segments has statistical significance in the distribution of TCM syndromes(P<0.05).8.among the three tumor markers,CEA increased in turn in the syndrome of retention of phlegm-dampness in lung(P<0.05),deficiency of both qi and yin(P<0.05),stagnation of qi and blood stasis,and retention of phlegm-dampness in lung(P<0.05),and retention of qi and blood stasis in water(p <0.05).NSE increased in turn on phlegm-dampness retention in lung,qi-yin deficiency,qi stagnation and blood stasis,and water retention in lung.The comparison between the two groups showed that there were significant statistical differences between water retention and qi-yin deficiency,water retention and qi stagnation and blood stasis,water retention and phlegm-dampness retention in lung(P<0.05).CYFRA21-1increased in turn in qi stagnation and blood stasis,deficiency of both qi and yin,retention of phlegm and dampness in the lung,and internal stagnation of water drinking.the comparison between the two groups showed that there were significant statistical differences between internal stagnation of water drinking and qi stagnation and blood stasis,internal stagnation of water drinking and deficiency of both qi and yin(P<0.05).Conclusion:1.primary lung cancer is characterized by deficiency of qi and yin,followed by stagnation of qi and blood stasis,phlegm and dampness accumulation of lung and stagnation of water.2.TCM syndrome type distribution in primary lung cancer was associated with tumor TNM staging,metastasis,pleural effusion,cardinality score and tumor markers(CEA?NSE?CYFRA21-1),but not with age,pathological type.tumor stage,metastasis,pleural effusion,KPS score and tumor markers can be used as indicators to assist TCM syndrome differentiation and classification of lung cancer.3.he patients with primary lung cancer,the syndrome type is mainly qi-yin deficiency type,which indicates that the tumor is easy to consume qi and injure yin after metastasis.