The Meta-analysis Of The Therapeutic Effect Of The Method Of Strengthening The Spleen And Qi In The Treatment Of Allergic Rhinitis And The Summary Of Professor Zhang Qinxiu's Experience In The Treatment Of Allergic Rhinitis

Objective : Use meta-analysis to evaluate the spleen and qi-enhancing methods: the efficacy of Buzhong Yiqi Decoction,Shenling Baizhu Powder,and Yupingfeng Powder in the treatment of allergic rhinitis,so as to provide evidence-based basis and reference for the clinical research and treatment of allergic rhinitis in the future.data source: By searching the following databases: CNKI,Wanfang database,China Science Citation Database,VIP database,Pub Med,Cochrane Library,we screened the randomized controlled trials of Buzhong Yiqi Decoction or Shenling Baizhu powder or Yupingfeng Powder in the treatment of AR.Methods: Screened literature for inclusion and exclusion criteria,and literature data were extracted.Standards and quality assessment methods based on Cochrane Review Handbook 5.0,the bias risk of each literature was comprehensively evaluated.The meta-analysis was carried out by Review Manager 5.3 software.Results: 21 randomized controlled clinical trials of invigorating spleen and invigorating qi in the treatment of AR were included,involving 2252 subjects.Only 7 papers describe how random sequences are generated,and the remaining 14 papers indicate "random" without specifying.Only one document was grouped by SPSS13.0 software,which achieved distribution concealment.Only one literature mentioned the use of "double-blind" research methods.Only two articles described the case of rejection or shedding.The results of literature quality bias show that the overall literature of this study has a high risk of bias.The method of strengthening the spleen and replenishing qi,compared with the conventional treatment of western medicine,has a high total effective rate,P <0.00001,RR = 1.18,95% CI is(1.14,1.23);the recurrence rate is low,P <0.01,RR = 0.38,95% CI is 0.21,0.68).There is no significant difference between the two groups in the improvement of symptoms and signs;the improvement of Ig E is more significant,and the improvement of IL-4 is not significantly different;In terms of adverse reactions,there was not much difference between the two groups.Conclusion: Compared with the conventional treatment of western medicine,invigorating spleen and Supplementing Qi method has higher efficiency and lower recurrence rate.The improvement of symptoms and signs and the improvement of laboratory indicators are equivalent to the conventional treatment of western medicine,and the adverse reactions appear to be equivalent to the conventional treatment of western medicine.Due to the small number of literatures included in this study,the experimental design lacks standardization,and the quality of the literatures is low,and the results of meta-analysis may be affected.