| Objective:To observe the effect of Yang yin Qingfei Mixture combined with Azithromycin on the recovery phase,symptom score and long-term efficacy of Mycoplasma pneumoniae pneumonia(MPP)in children,and to evaluate its preventive effect on MPP recovery phase.It provides new dialectical ideas for the consolidation of MPP recovery symptoms and recurrence of the disease.Material and method:The clinical data of children with Mycoplasma pneumoniae pneumonia(MPP)recovery period that met the inclusion criteria were randomly divided into treatment group A and control group B,30 cases in each group.Group B received sequential oral azithromycin treatment,and group A was orally administered with Yang yin Qingfei Mixture on the basis of sequential azithromycin.The treatment course was 14 days and the observation period was 6 months.Observe the following content of children in groups A and B before and after treatment in the recovery phase.For example,points for major symptoms and signs(cough,expectoration,fever)points for secondary symptoms(flushing of hands and feet,Night sweatsthirst,poor sleep,dry mouth,dry stool),total points,significant efficiency,adverse reactions And follow-up of respiratory infections.Results:1.After comparing the age,sex,height,weight,and pre-treatment symptom scores(main symptoms,secondary symptoms)of the children in the two groups of A and B,it was found that there is no significant difference between the two(P>0.05)and they are comparable.2.The comparison of the overall efficacy of the two groups of children showed that after treatment,the total significant effect of the observation group A group was 83%,the control group B was 60%,and the group A was significantly better than the group B.The difference in children was statistically significant(P <0.05).3.Comparing the scores of the main symptoms and secondary symptoms of the two groups of children,it was found that in the main disease score,on the 3rd and 7th days after treatment,group A was significantly lower than group B(P <0.05),and on day 10(except for hypothermia not analyzed),group A was significantly lower than group B(P < 0.05),on the14 th day(except for low fever),although group A was lower than group B,the difference between the two groups was not statistically significant(P> 0.05);Compared with those before treatment,the scores of the main symptoms on the 3rd,7th,10 th and 14 th days after treatment in the two groups of patients were significantly different(P <0.001);On day 3 and before treatment,day 7 and day 3,day 10 and day 7,respectively,the differences in the main symptoms of the two groups of children were statistically significant(P <0.05).The difference between day 14 and day 10 was not statistically significant(P> 0.05).On the secondary disease score,on the 3rd and 7th days after treatment,group A was significantly lower than group B(P <0.05).On the 10 th day,except for poor sleep and dry mouth,group A was significantly lower than group B(P < 0.05),on the 14 th day,in terms of hand-foot-heart fever and night sweats,group A was significantly lower than group B(P <0.05),while the other symptoms of group A were lower than group B,but not statistically significant(P>0.05);Compared with the pre-treatment scores of each symptom score on the 3rd,7th,10 th and 14 th days after treatment,the differences in group A children were significantly different(P <0.001);Comparing the 7th day with the 3rd day,the 10 th day with the 7th day,the 14 th day with the 10 th day,the differences in the changes of the secondary diseases in group A were statistically significant(P <0.05).Compared with before treatment on the third day after treatment,the children in group B were able to relieve sleep and dry stools,and alleviate the scores of secondary symptoms.The difference was statistically significant(P <0.05).Comparing day 7 with day 3,except for dry stool(P> 0.05),all had statistical significance(P<0.05);day 10 with day 7,day 14 with day 10,all had statistics Academic significance(P<0.05).4.After comparing the incidence of adverse reactions between the two groups,it was found that the incidence of adverse reactions in group A was 10%,the incidence of adverse reactions in group B was 16%,and that in group A was lower than that in group B,but the difference between the two groups was not statistically significant(P> 0.05).5.A half-year observation of the two groups of children found that during the 2-month and4-month follow-up,the incidence of respiratory infections in group A was lower than that ingroup B,and the difference between the two groups was statistically significant(P <0.05);During the 6-month follow-up,it was found that although the incidence of respiratory infectious diseases in group A was lower than that in group B,the difference between the two groups was not statistically significant(P> 0.05);Conclusion:1.Yang yin Qingfei Mixture combined with azithromycin has a good effect on MPP(yin deficiency lung heat syndrome)treatment,and is better than the azithromycin group alone.2.Yang yin qingfei Mixture combined with azithromycin can better relieve the symptoms of children and clinical syndromes of traditional Chinese medicine,reduce the occurrence of adverse reactions,and is safe and effective.3.Yang yin Qingfei Mixture combined with azithromycin in the treatment of MPP(yin deficiency lung heat syndrome)in children with follow-up out-of-hospital respiratory disease has a low recurrence rate and good long-term efficacy. |
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