Study On The Clinical Curative Effect Of Modified Compound Huangqi Decoction On Myasthenia Gravis Type ? And ? After Thymoma Surgery

Purpose:to observe the clinical efficacy of compound Huangqi decoction in the treatment of type I and II myasthenia gravis patients after thymoma operation,and to provide a new way of thinking and choice for this kind of patients to use traditional Chinese medicine in the treatment of myasthenia gravis.Material and method:From June 2017 to September 2018,60 patients with type I and II myasthenia gravis who met the inclusion criteria in the first affiliated Hospital of Liaoning University of traditional Chinese Medicine were collected and signed with informed consent.The patients were randomly divided into two groups:control group(n=30)and test group(n=30).There were 12 males and 18 females in the experimental group,with an average age of46.6 years,8 patients with AB thymoma and 22 patients with type B thymoma.In the control group,there were 16 males and 14 females,aged 22-68 years,with an average age of 49.4 years.There were 7 cases of type B thymoma and 23 cases of type B thymoma.The experimental group was treated with compound Huangqi decoction combined with bromopyrimine,while the control group was treated with bromopyrimine.Before and 6months after treatment,the absolute score table and TCM symptom scale of myasthenia gravis were evaluated.The data were statistically analyzed by SPSS20.0 software,and the improvement and difference of symptoms were observed from the aspects of absolute score,symptom score and thymoma classification.Results:1.General situation:the selection of thymoma postoperative I,II myasthenia gravis patients,a total of 60 cases.There were 28 males and 32 females,the youngest was 22 years old,the oldest was 73 years old,the average age was(48.02±12.664)years.Preoperative typing of thymoma included 15 cases of AB type and 45 cases of type B type.2.The MG scale showed that the total effective rate was 90%in the experimental group and53.33%in the control group.The comparison between the two groups before and after treatment was P<0.05,suggesting that both groups have curative effect.After treatment,Z=2.564,P<0.05,indicating that the curative effect of the experimental group was better than that of the control group.3.The total effective rate was 93.33%in the experimental group and 56.67%in the control group.The comparison between the two groups before and after treatment was P<0.05,suggesting that both groups have curative effect.After treatment,Z=3.395 and P<0.05,indicating that the curative effect of the experimental group was better than that of the control group.4.The effective rate of pathological classification of resected thymoma in the experimental group was 7 in the AB group and 20 in the B group.There was no significant difference in the effective rate between the two groups by chi-square test,X~2=0.076,P>0.05,suggesting that there was no significant difference in the effective rate between the two groups.Conclusion:1.The efficacy of compound Huangqi decoction combined with bromopyrimine in the treatment of type I and II myasthenia gravis after thymoma is better than that of bromopyrimine alone.2.There was no significant difference in the efficacy of compound Huangqi decoction combined with bromopyrimine in the treatment of MG patients with different types of thymoma.