Analysis Of The Differences In TCM Syndromes And Clinical Features Of Different Genders In Rheumatoid Arthritis

Purpose:To compare and analyze the differences in the distribution of TCM syndromes and clinical features between patients with rheumatoid arthritis(RA)of different genders,and to provide a theoretical basis for clinicians to make integrated Chinese and Western medicine treatment decisions.Material and method:A total of 159 hospitalized patients with rheumatoid arthritis were collected from the Department of Rheumatology and Immunology,Liaoning Provincial Hospital of Traditional Chinese Medicine,2018.6.1-2018.12.31.The patient's condition data were collected by clinical questionnaire and divided into two groups according to gender.There were 43 cases in the group and 116 cases in the female patient group.The clinical data of the two groups were compared and analyzed,such as: four diagnostic data of Chinese medicine,age of onset,combined with other diseases,laboratory test indicators(ESR,CRP,anti-CCP antibody),VAS(Visual analogue scale)score,DAS28 score,relationship between different TCM syndrome types and disease activity,and Health assessment questionnaire(HAQ)score,BMI,and affected joints.Results:1.Analysis of clinical data of traditional Chinese medicine: 1Comparing the five TCM syndromes that often appear in clinical practice,among which the frequency of males is higher than that of females in the syndrome of cold dampness and dampness and heat stasis syndrome,the difference is statistically significant(P <0.05);among the qi and yin deficiency syndromes,the frequency of females was higher than that of males,and the difference was statistically significant(P<0.05).There was no significant difference between male and female in liver and kidney deficiency type(P> 0.05);2 From the perspective of the tongue and vein,males showed reddish tongue,string pulse,and fine veins more than women,the difference was statistically significant(P<0.05),while female patients showed red tongue and tongue frequency.More men than men,the difference was statistically significant(P <0.05);3with systemic symptoms: female RA patients with dry eyes,fatigue symptoms more than male RA,the difference was statistically significant(P <0.05)male RA patients appeared The symptoms of fear of heat and sweat(sweating/sweeing)were more common than those of women,and the difference was statistically significant(P<0.05).2.Age of onset: According to the overall age of onset,the age of onset of female patients is between 20 and 77 years old,and the average age of onset is 49 years old.The age of onset of male patients is between 22 and 76 years old,with an average age of 54 years.In the age groups of 31-40 years old and 51~60 years old,gender factors did not affect the incidence rate(P>0.05).The incidence of female patients in 41-50 years old was higher than that of males.The male prevalence rate after 60 years old was higher.Females were high and the differences were statistically significant(P<0.05).3.From the point of view of concomitant diseases,women with RA were associated with osteoporosis and pulmonary fibrosis,and the difference was statistically significant(P<0.05).Male RA was associated with higher incidence of diabetes than females.The difference in the incidence was statistically significant(P<0.05).There was no significant difference in the incidence of male and female patients with coronary heart disease,hypertension,osteoarthritis and secondary Sjogren's syndrome(P>0.05).4.From the changes of blood system,there is no difference in blood system changes(any abnormality of platelets,white blood cells and hemoglobin)between males and females(P>0.05);however,the incidence of elevated platelets in men is higher than that of females.The significance of learning(P<0.05);there was no significant difference in HB and WBC between male and female RA patients(P>0.05).5.Relevant scores and laboratory tests: The scores of DAS28 and HAQ in female RA patients were higher than those in males,the difference was statistically significant(P<0.05),and different TCM syndromes were not related to disease activity,and the difference was not statistically significant(P>0.05);CRP and RF were significantly higher in male RA patients than in women,and the difference was statistically significant.There was no significant difference in VAS score,anti-CCP antibody and ESR between the two groups(P>0.05).Correlation analysis showed RA patients with male and female BMI is not related to DAS28.6.From the joints of different genders,the incidence of RA in both elbow joints and double wrists was higher in males than in males(P<0.05).Male RA was more common in female RA than female RA.The difference was statistically significant.Significance(P<0.05).Conclusion:1.Distribution of TCM Syndrome Types: In the type of cold dampness and dampness and heat stasis syndrome,the frequency of male occurrence is higher than that of females.In the syndromes of qi and yin deficiency and stagnation syndrome,the frequency of females is higher than that of males.2.Clinical manifestations: male RA with fear of heat,sweating(self-sweat / night sweats)is more common,red tongue,string pulse,fine veins appear more frequently than women;female RA patients are more likely to be associated with dry mouth,fatigue Symptoms of red tongue and licking tongue are more frequent than men;female RA has more elbow joints and double wrist joints than men,and male RA is more common than females.3.Age of onset: between 41-50 years old,the incidence of women is higher than that of men,and the incidence of men after 60 years is higher than that of women.4.Associated disease pattern: Female RA patients with osteoporosis and pulmonary interstitial fibrosis are more likely than men;and male RA is more likely to be associated with diabetes than women;associated with coronary heart disease,hypertension,osteoarthritis and secondary There was no difference in Sjogren's syndrome;there was no difference in blood system changes between men and women,but male RA was more likely to develop platelets than women.5.Laboratory indicators and related scores: Female patients' disease activity is generally higher than that of males,and different TCM syndromes have nothing to do with disease activity;male patients have higher CRP and RF values than females;and two groups have VAS scores,ESR,and antibiotics.There was no difference in CCP antibodies,and BMI was not associated with DAS28.