Study On The Medication Rule Of Cold Gastric Pain And Observation Of The Clinical Efficacy Of Nuanweizhitong Ointment

Purpose: With the cold epigastralgia literature research and mentor clinical experience to explore the prescription prescription department thought plaster of the stomach and observe the clinical symptoms before and after treatment.The clinical efficacy of drugs was analyzed and summarized for the stomach pain paste has the scientificity and rationality and provide a theoretical basis for it.Material and method: This paper is divided into two parts: theoretical research and clinical observation.In the field of theoretical research,it is mainly through the combing of ancient and modern literature.And summarize the clinical experience of tutor and put forward ideas Nuanwei plaster prescription,The summary of nearly 20 years of medical treatment of cold epigastralgia literature,The drug composition and drug laws are summarized,for stomach pain ointment prescription of scientific and reasonable to provide a theoretical basis.In the clinical observation,Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2016 to September 2017,the spleen and stomach in outpatient department in accordance with the inclusion criteria of cold epigastralgia in 85 patients as the research object.The course of treatment was 7 days,To observe the effect of pain relief,the change of pain score after treatment,and the changes of the main and secondary symptoms before and after treatment.Results: theoretical research results(1)The cold epigastralgia drug law 1.Frequency analysis:Cold pathogenic stomachache and its clamping syndromes have high frequency of medication,such as Liqi drugs,Huoxue drugs,and Jiebiao drugs,Wenli drugs,Huashi drugs and xiaoshi yao.2.Cluster analysis:Cold epigastralgia and medication and syndrome It includes eight categories:Liqi drugs,Huoxuehuyu drugs,Xiaoshi food,Zaoshihuatan drugs,Wenzhongsanhan drugs,Qingrehuasgi drugs,and Buyi drugs.3.Correlation analysis:Cold evil criminals drugs combination for stomachache are Gaoliangjiang? Xiangfu?Wuzhuyu? Sharen? Chenpi ?Fuling? Wuyao? Baihe? Danshen?Banxia?Gancao.The core drug combination of spleen stomach deficiency cold type epigastralgia are Huangqi?Gangshen?Fuling?Baizhu?Muxiang?Ganjiang?Chenpi?Banxia?Guizhi?Baishao?Dazao?Yitang?Huanglian?Shengjiang?Baihe?Wuyao?Gancao and so on.(2)Symptoms of cold stomachache:The summary of 120 cold epigastralgia literature concluded that cold-induced epigastric pain mainly includes the cold evil convicted stomach,spleen and stomach Deficiency cold two categories.The pathogenesis of a cold condensate qi stagnation as the center,and then produce phlegm,dampness,phlegm,deficiency all kinds of evidence;two with spleen and stomach yin deficiency as the center,weak stomach spleen,lifting lost Division,stagnate,dampness,blood stasis And other evidence.(?)Clinical observation results(1)Analgesic effect: After the treatment 0f one week,30 cases of stomachache patients were treated with cold pathogens,3 patients were completely relieved from the pain,21 patients were significantly relieved,and 6 cases were mildly relieved,the total effective rate is 100%;In 55 patients with epigastric pain,9 patients were completely relieved from the pain,25 patients were significantly relieved,and 21 patients were mildly relieved.The total effective rate was 100%.(2)Comparison of Pain Score: After 1 week of treatment,30 patients with cold stomachache cramps,4.53 points of pain before the treatment,and 0.93 points after the treatment,and the average difference is 3.60;stomach-deficiency type stomach cramps.In 55 patients with stomachache,the average score before the treatment is 4.64 points,and the average score is 1.02 after the treatment.The average difference is 3.62.Compared the scores before with after the treatment,and paired with the test showed that the pain scores of the patients are decreased significantly(P<0.01).(3)Comparison of TCM syndrome scores:After the treatment,30 patients with stomachacge were treated with cold pathogens.Before the treatment,scores of TCM syndromes are 241 and 55 points after the treatment;55 patients of stomach-ache with spleen-stomach-deficiency type,Before the treatment the total scores are 407 and 97 points after the treatment,the decrease rate was significant and the difference was very significant(P<0.01).Conclusion: The idea of Nuanweizhitong ointment is basically as same as the literature.The composition of the drug is reasonable and scientific.It has significant clinical curative effect on patients with cold stomachache and it is deserved to further promotion and application.