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Study On The Distribution Of TCM Syndrome Types Of Chronic Heart Failure With Atrial Fibrillation And The Prognosis Of BMI

Posted on:2020-06-10Degree:MasterType:Thesis
Country:ChinaCandidate:F L ChenFull Text:PDF
GTID:2434330575976869Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Clinical investigation IObjective:To analyze the TCM syndromes of patients with chronic heart failure(CHF)and atrial fibrillation(AF)by statistical analysis,to explore the distribution pattern of TCM syndromes in CHF patients with AF,and to develop effective,stable and long-term use for the syndrome differentiation of CHF combined with AF and further standardized treatment of traditional Chinese medicine.The foundation of Chinese medicine prescription or proprietary Chinese medicine.Methods:A retrospective study was conducted to analyze the TCM syndromes of patients with CHF and AF who were hospitalized in the Department of Integrative Medicine,China-Japan Friendship Hospital from April 2011 to April 2018,and analyzed the CHF merger by descriptive analysis.The distribution pattern of TCM syndrome types in patients with AF.Results:1.A total of 80 patients with CHF and AF were enrolled in this study.The medical syndrome type was analyzed.There are 7 main TCM syndrome types:21-cases of qi deficiency and blood stasis syndrome(26.2%)and 13 cases of phlegm and blood stasis syndrome(.16.3)%),Yang deficiency water syndrome in 11 cases(13.7%),Qi and Yin deficiency syndrome in 9 cases(11.2%),phlegm and blood stasis syndrome in 9 cases(11.2%),heart and kidney yang deficiency syndrome in 4 cases(5.0%)4 cases(5,0%)of spleen and kidney yang deficiency,other syndromes of phlegm-heat syndrome,cardio-qi deficiency syndrome,qi stagnation and blood stasis syndrome.2.According to the syndrome differentiation of traditional Chinese medicine,22 cases(27.5%)of patients with CHF and AF were confirmed by this study,26cases(32.5%)were confirmed by evidence,and 34 cases(40.0%)were false and mixed syndromes.Conclusions:1.There are 7 kinds of syndromes of CHF combined with AF:qi deficiency and blood stasis syndrome,phlegm and water stasis syndrome,yang deficiency water syndrome,qi and yin deficiency syndrome,phlegm and blood stasis syndrome,heart and kidney yang deficiency syndrome,Spleen and kidney yang deficiency,among which qi deficiency and blood stasis syndrome and phlegm and water stasis syndrome are the most common.2.CHF combined with AF patients with the virtual standard,false and real mixed syndrome,followed by pure evidence,the least deficiency syndrome.Clinical investigation ?Objective:To analyze the relationship between BMI and CHF combined with AF in patients with CHF and AF,and to explore the optimal BMI range of patients with CHF combined with AF,in order to provide a clinical reference for weight management of CHF combined with AF.Methods:This study followed 188 patients with CHF and AF who were admitted to the Department of Cardiology and Cardiology of China-Japan Friendship Hospital from April 2011 to April 2018,with all-cause death and major adverse cardiovascular events(MACE).)for the end of follow-up.Patients were divided into 4 groups according to BMI:low body recombination(BMI<18.5kg/m2),normal body recombination(18.5BMI<24kg/m2),super recombination(24?BMI<28kg/m2),obesity group(BMI)?28kg/m2).First,compare the differences between clinical indicators and endpoint events between different BMI groups.Kaplan-Meier curve and Log-rank test were used to describe and compare the all-cause mortality and MACE incidence in different BMI populations.Multivariate Cox regression was used to analyze the independent predictive effect of BMI reduction on the prognosis of patients with CHF combined with AF.Comparison of death risk in the BMI population.Results:1.188 patients with CHF combined with AF were followed up,173 patients(92.0%)were followed up,15 patients(8.0%)were lost to follow-up,49 patients(28.3%)died of all-cause,and 60 patients(34.7%)developed MACE.The median follow-up time was 1424.5 days.There was a statistically significant difference in the cumulative survival rate between the different BMI groups(log-rank=9.465,P=0.024).There was no statistically significant probability of MACE accumulation(log-rank=0.094,P=0.993).2.COX proportional hazard regression model After adjusting for other factors,the all-cause mort,ality risk of low body reorganization was 1.120times(95%CI:0.868-1.411,P=0.008)in the obese group,and 0.481 times in the normal group in the obese group.95%CI:0.153-1.051,P=0.041)?super-recombination was 0.496-fold(95%CI:0.185-1.110,P=0.033)in the obese gr oup.BMI reduction was not an independent predictor of all-cause mortality in patients with CHF and AF.Conclusions:1.BMI control in patients with CHF combined with AF is beneficial to reduce all-cause mortality between 18.5-28 kg/m2.2.CHF combined with AF patients with all-cause mortality risk and overweight<obese<low weight.
Keywords/Search Tags:chronic heart failure, atrial fibrillation, TCM syndrome, body mass index, prognosis
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