| ObjectiveTo observe the clinical effect of aromatherapy on the treatment of the insomnia of the liver-depression and spleen-deficiency type,the traditional aromatic external treatment method is used to improve the sleep condition of the patients with insomnia and the effectiveness and the advantages of the traditional Chinese medicine syndrome,so as to provide a new thought and a new treatment method for the treatment of the insomnia by the traditional Chinese medicine.And also provides the basis for clinical application of the aromatherapy.Methods60 cases of liver-depression and spleen-deficiency type insomnia were randomly divided into 30 cases of sleep and 30 cases of placebo group by means of the social integration of the Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine.The method of intervention:before going to bed every night,place the sachet within 30 cm from the head,and seal the sachet with a plastic sealing bag in the morning to prevent the effective component from volatilizing.The treatment course was 28 days,and the clinical efficacy was evaluated by using the clinical observation questionnaire(SPIEGEL),the Pittsburgh Sleep Scale(PSQI)and the TCM syndrome scale on the day of entry,the second week and the fourth week,respectively.ResultsSPIEGEL score:after 2 weeks of treatment,the scores of other items were decreased in the sleep capsule group except for the dream condition.In the placebo group,the scores of sleep depth,wake-up sensation and total score were lower than those in the placebo group(P<0.05),and that in the placebo group was significantly lower than that in the control group(P<0.05).In the second week after treatment,the sleep sacs group was better than the placebo group in terms of SPIEGEL score,sleep time,total sleep time and wake-up several times(P<0.05),but no significant difference was found between the control group and the placebo group(P<0.05).After 4 weeks of treatment,the scores of sleep capsule group were all decreased and had statistical significance(P<0.05).The scores of sleep time,sleep depth and total score were decreased in placebo group(P<0.05),and the scores of sleep duration,sleep depth and total score in placebo group were significantly lower than those in control group(P<0.05).In the fourth week after treatment,the sleep sacs group was better than the placebo group in terms of SPIEGEL score,sleep time,total sleep time and wake-up scores(P<0.05).In the sleep capsule group,the scores of the second week and the fourth week after treatment were better than those of the second week in reducing the single score of dream condition.In summary,at week 2,sleep sacs improved sleep time,total sleep time,and awakened several times better than placebo group.4 weeks,sleep sacs improved sleep time,total sleep time,awakened several times than placebo capsule group,from week 2 to week 4,the sleep sacs improved sleep time,and the total sleep time was better than that of placebo capsule group,from week 2 to week 4.There has been a further improvement in dream conditions.PSQI score:after 2 weeks of treatment,the scores of sleep time,sleep time,sleep efficiency,sleep disturbance,daytime function and total score of the group were decreased(P<0.05),and the scores of sleep quality in the placebo group decreased(P<0.05).The scores of PSQI and sleep time,sleep time and sleep disorder were superior to the placebo group(P<0.05)at the second week after treatment.After 4 weeks of treatment,the sleep quality,the time of sleep,the sleep time,the sleep efficiency,the sleep disorder and the total score of the group were decreased(P<0.05),and the scores of the placebo group in the sleep quality decreased(P<0.05).The scores of PSQI and the time of sleep,sleep time,sleep efficiency and sleep disorder were superior to that of the placebo group(P<0.05)at the 4th week after treatment.The scores of the second week and the fourth week after the treatment of the group were better than that in the second week(P<0.05).in that first and second week,the sleep time,the sleep time and the sleep disorder were better than that of the placebo group,the sleep time,the sleep efficiency and the sleep disorder were better than that of the placebo sachet group,from the second to the fourth week,And the sleep time and the sleep efficiency are further improved.TCM syndrome score:after 2 weeks treatment,the score of insomnia,chest pain,less food,headache and total score decreased in the sleep capsule group(P<0.05),and the score in the placebo capsule group decreased in the chest tightness pain(P<0.05).In the second week after treatment,the sleep capsule group was better than the placebo group in reducing TCM syndrome score and insomnia,irritability and eating less than placebo group(P<0.05).After 4 weeks of treatment,the scores of insomnia,chest tightness,multiple dreams,irritability and loose stool were decreased in the sleep capsule group(P<0.05),and those in the placebo group were lower than those in the placebo group(P<0.05).At the4th week after treatment,the score of TCM syndrome,insomnia,chest pain,multiple dreams,irritability and loose stool in the sleep capsule group were significantly lower than those in the placebo group(P<0.05).Compared with the scores of TCM syndrome in the second week and the fourth week after treatment in the sleep capsule group,the fourth week was superior to the second week in reducing insomnia,irritability and the total score of three items(P<0.05).In summary,2 weeks,sleep sacs improve insomnia,irritability,eating less than placebo sacs group,fourth week,sleep sacs improve insomnia,chest tightness,multiple dreams,irritability,loose stool than placebo sacs group.From week 2 to week 4,insomnia,multiple dreamsirritability and irritability have further improved.The clinical curative effect of insomnia:in the second week after treatment,the effective rate was 10 cases,the remarkable effect was 9 cases,the total effective rate was 63.33%in the sleep capsule group.The total effective rate in placebo group was 20.00%,the former was higher than that in the latter.In the fourth week after treatment,there were 12 effective patients in the sleep capsule group,and the total effective rate was 53.33%,while in the placebo group,the total effective rate was 13.33%,and the effective rate in the placebo group was 13.33%,and the effective rate in the placebo group was significantly higher than that in the control group(P<0.05).The results showed that the curative effect of sleep capsule group was significantly better than that of placebo group at the 4th week after treatment.The total effective rate was 63.33%in the second week,53.33%in the fourth week,and was lower in the 4th week than in the 2nd week,compared with that in the 2nd week,and the total effective rate was 63.33%in the 2nd week and 53.33%in the 4th week,respectively.But there was no statistical significance(P>0.05).In conclusion,the clinical effect of sleep sacs was significantly better than that of placebo group.The curative effect of TCM syndrome of insomnia:in the second week after treatment,the effective rate was 16.67%in the sleep capsule group and 3.33%in the placebo group,and the former was higher than that in the latter group(P<0.01),and the total effective rate was 16.67%in the sleep capsule group and 3.33%in the placebo group.In the fourth week after treatment,the total effective rate was 36.67%in the sleep capsule group and 3.33%in the placebo group,the former was higher than that in the control group(P<0.05),and the total effective rate was 36.67%in the sleep capsule group and 3.33%in the placebo group at the 4th week after treatment.The total effective rate was 36.67%in the second week and 3.33%in the fourth week in the sleep capsule group.The clinical effective rate in the fourth week was higher than that in the second week.There was no significant difference in the total effective rate between the second week and the fourth week.To sum up,the TCM syndrome effect of sleep sacs is superior to placebo group.In conclusion,the clinical curative effect and TCM syndrome effect of sleep sacs on insomnia of liver depression and spleen deficiency type were obviously higher than those of the control group,in addition,placebo had some consolation effect.ConclusionsThe sleeping capsule can effectively reduce the SPIEGEL score,the PSQI score and the integral of the traditional Chinese medicine syndrome in the patients with insomnia,and has a more obvious clinical effect on the liver-depression and spleen-deficiency type insomnia and the curative effect of the traditional Chinese medicine syndrome;and the placebo sachet has a certain comfort effect;There was no significant difference in the efficacy of the second week and the 4th week after the use of the capsule.The combination of external aromatic therapy and TCM syndrome to treat insomnia of liver-stagnation and spleen-deficiency type has obvious effect.It provides a new thought and new treatment method for the study of insomnia and provides objective basis for the clinical effect of aromatherapy.On this basis,we can also expand the scope of use of aromatic drugs,accumulate valuable experience for the follow-up research on aromatherapy for other diseases,and take this opportunity to return the traditional aromatherapy in China back to people's horizons.Inherit and carry forward the traditional treatment method of traditional Chinese medicine to relieve the pain for more patients. |
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