Analysis Of Clinical Diagnosis And Treatment Of 98 Cases Of Pancreatic Cancer

Background:Pancreatic cancer is a devastating malignancy,with an overall 5-year survival rate of 8%at all stages,mainly because the symptoms of pancreatic cancer are not obvious.Currently,there is no auxiliary examination method for the specific diagnosis of pancreatic cancer,and pathological examination can be diagnosed,but it is not conducive to the early diagnosis of pancreatic cancer.Currently,surgical resection is the only curative treatment for patients with resectable pancreatic cancer.Unfortunately,80%to 85%of patients are diagnosed with locally advanced or metastatic pancreatic cancer.How to diagnose and treat pancreatic cancer as early as possible,and how to prolong survival is still a huge challenge for clinicians.Objective:Through retrospective discussion on the history of initial symptoms,auxiliary examination,surgical treatment of 98 patients with pancreatic cancer,a deeper understanding of the entire diagnosis and treatment process of pancreatic cancer in recent years can be obtained,and provid clues for better surgical treatment of pancreatic cancer.Methods:Choose between January 2016 and December 2017,our first diagnosed with pancreatic cancer by pathology examination of 98 patients,98 cases of patients with medical record often were retrospectively analyzed,mainly including starting symptoms,starting symptoms to diagnosis,pathological classification and staging,metastasis,auxiliary examination,treatment and postoperative complications,etc.;Another 98 patients were followed up for 4-28 months to analyze their survival after treatment,and the entire treatment process of pancreatic cancer was analyzed in detail.SPSS 20.0 statistical software was used for data analysis,and percentage(%)was used to represent counting data.Mean ± standard deviation(X±S)was used to describe the measurement data and t test was used to compare the differences.The measurement data of non-normal distribution were described by the median,and its differences were compared by the m-w test,where P>0.05 was not statistically significant,and P<0.05 was statistically significant.Results:1.There were 5 primary symptoms in 98 patients with pancreatic cancer,namely,anorexia,epigastric pain,emaciation,jaundice,and low back pain.Appetite loss was the majority,accounting for 31.6%of the total number;2.98 cases of patients using ultrasound and the examination of tumor,84.7%of patients using the CT examination,other also used magnetic resonance imaging(MRI),ultrasound,CT or MRI joint inspection tumor markers,and compared with pathology results,used in combination with a variety of auxiliary examination has the highest accuracy,as high as 91.4%,CT examination accuracy is as high as 90.2%;3.Among the 98 patients,69.4%were pancreatic head carcinoma.Low differentiated pancreatic cancer was 57.1%.The most III period of pancreatic cancer,36.7%;Metastasis occurred in 29.5%of patients,mainly liver metastasis and abdominal metastasis;4.38.7%of the patients underwent radical surgery,and the rest received cryoablation(34.7%)and palliative treatment(26.5%);5.30.5%of the patients had postoperative complications,with gastric emptying disorder and pancreatic fistula more common;6.Median survival was 15.5 months in patients treated with eradication,the longest of the three treatment regimens.Conclusion:Eradication of pancreatic cancer surgery the longest survival,but many patients because of from the onset symptoms to the diagnosis of pancreatic cancer of time is too long,lost the opportunity to eradicate,so when the clinical doctors in clinic found in patients with long history of anorexia,epigastric pain and angular,will be highly pay attention to the occurrence of pancreatic cancer.In order to better diagnose pancreatic cancer and create opportunities for radical surgical treatment,patients should be recommended to use b-mode ultrasound,CT or MRI combined with tumor markers for examination when fully communicating with patients.For patients with limited economy,CT can be selected for pancreatic cancer screening.Patients undergoing surgery for pancreatic cancer should pay attention to postoperative complications such as gastric emptying disorder and pancreatic fistula,so as to extend the survival period of pancreatic cancer patients and improve their quality of life.