Clinical Effect Of Xiaoyong Recipe On The Initial Stage Of Lactation Mastitis And Its Effect On Milk Flora

Objective:In this study,a prospective randomized controlled study was conducted to observe the clinical effect of Xiaoyong recipe on external blowing carbuncle and the effect on lactobacillus flora in the initial stage by comparing it with cefdinir treatment.Methods:Patients with 81 exceptions with primary breast abscess were randomly assigned to the control group: treatment group = 1:2.In the control group,27 patients were given oral cefdinir capsules,and in the treatment group,54 patients were given Xiaoyong recipe granules(added or decreased with the syndrome),and all were given external application of golden yellow ointment for 3 days.To observe and compare the quantitative score of breast carbuncle symptoms and signs,clinical efficacy,blood routine,CRP,positive rate of bacteria in breast milk of the affected side and the number of lactobacillus(streptococcus,staphylococcus,lactobacillus)in the two groups.Results:Signs and symptoms of two groups of patients with breast carbuncle quantitative total score were significantly reduced after treatment(P < 0.001),of which the breast pain,skin redness,tumor size,tumor number,body temperature,percentage of neutrophils and CRP in all kinds of integral were significantly reduced after treatment(all P < 0.05),and the tumor size and number of the treatment group than the control group of integral reduced more significantly(all P < 0.05).The recovery rate of the treatment group was 62.9%,significantly higher than that of the control group(25.9%)(P < 0.01).The number of leukocytes and the percentage of neutrophils in the blood of patients in both groups were significantly reduced after treatment(all P < 0.01).The CRP value of patients in the treatment group was significantly decreased after treatment(P < 0.01),while that in the control group was not significantly changed(P > 0.05).The positive rate of bacteria in the control group was 25.9% before treatment,in which staphylococcus aureus and staphylococcus epidermidis were the most(both were 11.1%).After treatment,the positive rate of bacteria was 22.2%,all of which were staphylococcus epidermidis.The positive rate of bacteria in the treatment groupwas 22.2% before treatment,and staphylococcus aureus was the most(14.8%).The positive rate of bacteria was 16.7%(P < 0.05).The number of the three bacteria(streptococcus,staphylococcus,lactobacillus)in both groups decreased after treatment compared with that before treatment,but the before and after treatment were not statistically significant(all P > 0.05).The reduction values of the three bacteria in the treatment group were smaller than those in the control group,but there was no statistical significance(P > 0.05).Further analysis and comparison of the patients recovered after treatment showed that the number of streptococcus after treatment was lower than that before treatment in the patients cured by cefdinir(P < 0.05),while the decrease of staphylococcus and lactobacillus was not significant(all P > 0.05).In the patients cured by Xiaoyong recipe,the quantity of the three kinds of bacteria decreased after treatment compared with that before treatment,but there was no statistical significance(all P > 0.05).The amount of lactobacillus was the most in the two groups before and after treatment(P< 0.05).Conclusion:1.Xiaoyong recipe for external blowing breast carbuncle at the initial stage of the recovery rate,by regularing qi and promoting blood circulation,is significantly higher than cefdinir,and the effect of dissipating the cefdinir was more significant than that of cefdnil.2.In the early stage of external blowing breast carbuncle,the bacteria positive rate of the breast milk of the patients on the affected side was low,mainly staphylococcus aureus,Xiaoyong recipe and cefdeni could reduce the positive rate of the bacteria in the breast milk.Before and after treatment,lactobacillus in the milk of patients in the two groups was more than that of patients in the two groups.After treatment,the reduction of streptococcus,staphylococcus and lactobacillus was not significant.