The Safety And Effectiveness Of The LVIS Stent For The Treatment Of Acutely Ruptured Intracranial Aneurysms Within The Hyperacute Phase

Objectives:To evaluate the safety and effectiveness of intracranial wide-necked aneurysms using low-section visualization intraluminal support stent(LVIS)assisted coil embolization treatment within 24 hours after rupture(super-acute phase)and compare the efficacy and safety of 25-72 hours after rupture treatment group(acute phase).Methods:This study is a retrospective multicenter study of the use of LVIS stent-assisted coil embolization in the treatment of acute ruptured intracranial wide-necked aneurysms in the hyperacute phase.Data were collected from all patients with intracranial ruptured aneurysm who were treated with LVIS stent-assisted coil embolization within 72 hours after the first subarachnoid hemorrhage.Hyperacute treatment is defined as interventional embolization within 24 hours after subarachnoid hemorrhage,while acute phase treatment is defined as interventional embolization within 25 to 72 hours after subarachnoid hemorrhage.The baseline characteristics,perioperative complications,angiographic results and clinical outcomes of the two groups were statistically analyzed.Results:All 101 patients with acute ruptured aneurysm received treatment within 72 hours,of which 49(48.5%)patients received LVIS stent-assisted spring embolization within 24 hours of the hyperacute phase,52 patients received same treatment within25 to 72 hours of acute phase;16(15.8%)patients were diagnosed with multiple aneurysms;There was no statistical difference between the two groups in terms of age,gender,preoperative WFNS grade,preoperative Fisher grade,and aneurysm characteristics.Intraoperative complications occurred in 7 cases(6.9%),and postoperative complications occurred in 5 cases(5%).Among them,2 patients(4.1%)developed perioperative complications in the hyperacute phase(within 24 hours)group,and 10 patients(19.2%)experienced perioperative complications in the acute phase(within 25-72 hours)group,the difference between the two groups are statistically significant.The total aneurysm occlusion rate for immediate angiography was 90.1%,and the total aneurysm occlusion rate for the most recent follow-up was96.4%.There were no significant differences in degree of aneurysm embolism and clinical outcome between the hyperacute phase group and the acute phase group.Conclusions:In the hyperacute phase(within 24 hours),the treatment of LVIS stent-assisted coil embolization for acute rupture of intracranial wide-necked aneurysms is safe and effective.The incidence of perioperative complications is low,the rate of immediate total embolism is high and the follow-up results are stable.