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Clinical Efficacy Of Ozone In The Treatment Of Acute Cerebral Infarction And Its Effect On Serum NSE And IL-6

Posted on:2021-05-27Degree:MasterType:Thesis
Country:ChinaCandidate:Z H ChiFull Text:PDF
GTID:2404330626465962Subject:Neurology
Abstract/Summary:PDF Full Text Request
ObjectiveBy comparing the NIHSS scores of patients in the experimental group and the control group before and after ozone treatment,the clinical effects of ozone in the treatment of acute cerebral infarction were observed.The neuron-specific enolase(NSE)and interleukin-6 IL-6)content,to explore the possible mechanism of ozone in the treatment of acute cerebral infarctionMethodsThe study included 60 patients with acute cerebral infarction diagnosed in the Department of Neurology of the Central Hospital of Shenyang Medical College and admitted to the hospital in 2019.They were divided into 30 experimental groups and30 control groups according to the random number table method.Platelet aggregation,improvement of cerebral circulation,lipid-lowering and stable plaque,etc.The experimental group was given ozone treatment on the basis of the control group.On the 1st and 10 th days of the treatment,the two groups of patients were evaluated by the NIHSS score,the changes in the two groups were compared,and the clinical effect of ozone on acute cerebral infarction was observed.The serum levels of NSE and IL-6 in the two groups of patients were detected and compared on the 1st and10 th days,respectively,and the possible mechanism of ozone treatment for acute cerebral infarction was explored.ResultsBefore the ozone treatment,there was no significant difference in the NIHSS score between the control group and the experimental group,P> 0.05;after treatment,the NIHSS score of the experimental group was significantly lower than the control group,and the difference was statistically significant,P <0.01;Comparison of serum NSE and IL-6 levels in the experimental group was statistically significant,P <0.01,while the difference in the control group was not statistically significant,P> 0.05;before the ozone treatment,there was no difference in the comparison between theexperimental group and the control group Statistical significance,P> 0.05,and after treatment,P <0.05,the difference was statistically significant.ConclusionsGiving ozone treatment to patients with acute cerebral infarction can reduce the patient's NIHSS score and reduce the levels of NSE and IL-6 in the patient's serum,which proves that ozone has a significant effect on acute cerebral infarction,has brain protective effects,can promote the recovery of neurological function,and reduce the inflammatory response.To improve patient prognosis.
Keywords/Search Tags:Ozone, acute cerebral infarction, efficacy, mechanism
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