Risk Factors Of Surgical Site Infection After Primary Total Knee Arthroplasty

Objective To analyze the risk factors of surgical site infection(SSI)in patients undergoing primary total knee arthroplasty(TKA)in our department,in order to provide a reference for clinical work.Methods A retrospective analysis was performed on the general date of all 1462 patients who underwent total knee arthroplasty for the first time in our department from January 1,2011 to December 31,2018 due to knee osteoarthritis.Our study Strictly based on the definition of surgical site infection(SSI),inclusion and exclusion method,28 cases in test group and 1434 cases in control group were selected,collect statistics on the age,sex,body mass index(BMI),urine test results,allogeneic blood transfusion,length of hospital stay and whether they have diabetes,rheumatoid disease,pulmonary infectious diseases(COPD,etc.),cardiovascular disease,lower extremity vascular disease,liver disease(viral hepatitis,cirrhosis,etc.)and other related information,SPSS 22.0 single factor analysis was used to analyze the statistically significant results.Logistic and Poisson regression analysis was used to determine the influence factors.P<0.05 considered the results to be statistically significant.Results The overall infection rate of the surgical site after total knee arthroplasty in our department was 1.9%.Univariate analysis showed patients in the two groups were obesity(BMI > 28),combined with rheumatoid disease,long-term history of hormone use,ASA grade ? ?,asymptomatic bacterial urine before surgery,allogeneic blood transfusion,preoperative longer hospitalization(>14days),total length of hospital stay(preoperative and postoperative),combined liver disease(viral hepatitis,liver cirrhosis,etc.)and pulmonarydiseases(COPD,etc.)were statistically significant(P<0.05).Logistic and Poisson regression analysis showed that allogeneic blood transfusion,long-term hormone use history before surgery,hospitalization time ? 14 days,asymptomatic bacterial urine before surgery,combined with pulmonary infectious diseases(COPD,etc.)and liver disease(viral hepatitis,cirrhosis,etc.)were influence factors for SSI.Conclusion The risk factors for surgical site infection after primary total knee arthroplasty are complicated,including allogeneic blood transfusion,long-term history of preoperative hormone use,preoperative hospital stay?14 days,preoperative asymptomatic bacteriuria,patient with pulmonary infectious diseases(COPD,etc.)and liver diseases(viral hepatitis,cirrhosis,etc.)have a relatively high risk of developing SSI after surgery.