| Objective: 1.To understand the differences in the level of blood glucose,blood lipids,BMI,Cystatin C,uric acid,homocysteine and ba PWV among the people with normal blood pressure,high-normal blood pressure and hypertension.2.To analyze the correlation between the value of ba PWV and the level of BMI,blood glucose,blood lipid,uric acid,cystatin C and homocysteine in the people with high-normal blood pressure and investigate the influencing factors of the value of ba PWV.Methods: According to the inclusion and exclusion criteria,62 patients with high-normal blood pressure who attended the physical examination center of our hospital from February to August 2019 were enrolled.At the same time,62 patients with normal blood pressure who attended to our hospital during the same period were selected,as well as those with hypertension.We collected their information included the general information,the value of some sercological indexes like fasting blood glucose(FBG),total cholesterol(TC),Triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),uric acid(UA),homocysteine(HCY),cystatin C(Cys C),neutrophil-lymphocyte ratio(NLR).The value of ba PWV(Brachial-ankle Pulse wave velocity)was measured by the atherosclerosis diagnostic device.Analyze the differences of the general information,the level of every above sercological index,every value of ba PWV among the three groups.At the same time,the correlation between the value of ba PWV and the level of every above sercological index in the patients with high-normal blood pressure was analyzed.At the end,analyze the correlation between the value of ba PWV and the level of every above sercological index in the patients with high-normal blood pressure by multiple linear regression to investigate their relationship.Results: 1.The result of the study that the differences in value of BMI between the patients with normal blood pressure,high-normal blood pressure,and hypertension was that the value of BMI in the patients with high-normal blood pressure and the hypertension were significantly higher than those with normal blood pressure group.(p<0.05).2.The result of the study that the differences in the level of TC,TG,LDL,fasting blood glucose,UA,Cys C,ba PWV between the patients with normal blood pressure,high-normal blood pressure,and hypertension was that the level of every above sercological index in the patients with high-normal blood pressure and hypertension was significantly higher than the patients with normal blood pressure(p <0.05).There was no statistical difference in the level of every sercological index between the patients with high-normal blood pressure and the hypertension(p> 0.05).The difference in the level of HCY between the three groups was statistically significant,and the level of HCY increased in turn(p <0.05).3.The value of ba PWV in the patients with high-normal blood pressure was correlated with the level of age,BMI,systolic blood pressure,cystatin C,and homocysteine.4.The result of the multiple linear regression analysis showed that the value of age,BMI,SBP,and cystatin C were the influencing factors of the value of ba PWV in the patients with high-normal blood pressure.Conclusion: 1.Compared with the people with normal blood pressure,those with high-normal blood pressure and those with high blood pressure have more chance to accompany with overweight,abnormal glucose and lipid regulation.2.The people with high-normal blood pressure and hypertension have a higher risk of cardiovascular events than those with normal blood pressure,and they should be intervened as soon as possible.3.In the people with high-normal blood pressure,the value of ba PWV was significantly related to the level of age,BMI,systolic blood pressure(SBP),and cystatin C.With increasing the level of age,BMI,systolic blood pressure and cystatin C,the arterial stiffness increased. |
