The Influence Of Oats On Intestinal Flora For Gestational Diabetes Pregnant Women

Objective:We aim to understand the advantage bacterium group in gestational diabetes pregnant women intestinal flora and the influence of the pregnancy outcome as well as differences through nutrition intervention and oat products for gestational diabetes intestinal flora.Methods:1.This is a cross-sectional study in GDM pregnant using Illumina Alpha high-throughput sequencing to detect the intestinal flora species diversity and superiority strains.2.This is an open random control trial in control group and oat group,compared two groups of intestinal flora species diversity and superiority strains through diet intervention and oatmeal intervention.3.To analyze the clinical effect of differences between the two groups through diet intervention and oatmeal intervention.4.To analyze the pregnancy outcomes of differences between the two groups through diet intervention and oatmeal intervention.Results:1.59 cases of GDM and 69 cases of healthy pregnant women were recruited,34 cases as control group,25 cases oats.26 cases of newborns,of which 10 cases as control group,16 cases of oat group.2.The intestinal flora richness in GDM pregnant women decreased significantly.There were statistically increases in the numbers of Bacteroidetes,and reductions in the numbers of Burkholderiales,Neisseria,Lactobacillales and Bacillales,respectively.3.After the intervention,oats group of intestinal flora Alpha diversity increased.There were statistically increases in the numbers of Roche,Rumen bacteria and reduction in the numbers of Clostridium,respectively.4.There was a significant effect on Oatmeal intervention to control postprandial blood glucose and slow down weight gain.A significant negatively correlation was found between body weight growth rate and oat completion.5.Oatmeal intervention had no obvious effect on the GDM pregnant women pregnancy outcome.Conclusion:There are significant differences between GDM and healthy pregnants in intestinal flora.Significant and positive effect on intestinal flora species diversity and superiority strains for GDM through oatmeal intervention.Oats play a positive role in postprandial blood glucose and body weight growth.