Analysis The Related Factors Of Pleural Effusion After Resection Of Primary Liver Cancer And Prevention

Objective: To investigate the related influencing factors of pleural effusion after resection of primary liver cancer,and find out the prevention and treatment measures to guide clinical work.Methods: Data of 173 patients who underwent hepatectomy in the Department of Hepatobiliary Surgery,the First Affiliated Hospital of Jinan University from January 2011 to January 2019,and were diagnosed as primary liver cancer by postoperative pathological examination,including patient factors and tumors Factors,surgical factors,postoperative related factors,a total of 37 related items of data,according to whether the postoperative pleural effusion was divided into two groups.First,through the univariate analysis and screening out the factors associated with postoperative pleural effusion,and then through the logistic regression analysis further explored independent risk factors for pleural effusion after resection of primary liver cancer.Results:(1)Univariate analysis showed: intraoperative blood loss,operation time,intraoperative blood transfusion,surgical site,tumor diameter,hepatic occlusion time,total intraoperative fluid infusion,postoperative ascites volume and 1 week postoperatively mean albumin may be associated with postoperative pleural effusion(P<0.05);Gender,age,smoking history,history of viral hepatitis,cirrhosis,liver function Child-Pugh classification,hypertension,diabetes,heart Vascular disease,preoperative TACE,preoperative liver cancer complications,ASA grade,preoperative serum total bilirubin,preoperative albumin,preoperative ALT,prothrombin time,creatinine,preoperative hemoglobin,platelet count,white blood cells count,tumor type,whether multiple tumors,whether laparoscopic liver cancer resection,whether anatomical hepatectomy,whether to rehydrate 500-1000 ml 6h before surgery,serum TBil,ALT,and HGB 1 week after surgery were no significant correlation with postoperative pleural effusion(P>0.05).(2)Multivariate logistic regression analysis was performed on the factors with P <0.05.The results showed that the surgical site,postoperative ascites volume and 1 week postoperatively mean albumin were the independent risk factors for the formation of postoperative pleural effusion(P<0.05).Conclusion: The pleural effusion after resection of primary liver cancer may be related to intraoperative blood loss,operation time,intraoperative blood transfusion,surgical site,tumor diameter,hepatic occlusion time,total intraoperative fluid infusion,postoperative ascites volumeand 1 week postoperatively mean albumin.The surgical site,postoperative ascites volume and 1week postoperatively mean albumin were independent risk factors for pleural effusion.In addition,cirrhosis may also be related to the formation of postoperative pleural effusion.