| Objective:To study the effects of progressive muscle relaxation training on depression,sleep quality and quality of reproductive life in patients with repeated embryo implantation failure,as well as the effect on clinical pregnancy and serum cortisol.Assess the satisfaction of patients with progressive muscle relaxation training.Methods:In this study,84 patients with Repeated Implantation Failure(RIF)who met the criteria for treatment in a reproductive center of a tertiary hospital in Lanzhou from April 2019 to September 2019 were selected as the study subjects.Grouped by study time,the intervention group(42 cases)was selected from April 2019 to June 2019,and the control group(42 cases)was selected from July 2019 to September 2019.Both groups were treated with the same treatment.The control group was given routine care,and the intervention group was given progressive muscle relaxation training on the basis of routine care,which started when the RIF patient entered the cycle,once a day,25-30 minutes each time,to the day before the patient's embryo transfer.All included patients were surveyed before the intervention(start date of the freeze-thaw cycle)with general information,Self-Depression Rating Scale(SDS),Pittsburgh Sleep Quality Index Scale(PSQI),Fertility Quality of Life Questionnaire(FertiQoL),and the morning serum of patients was collected for serum cortisol(COR).After the intervention(one day before the embryo transfer),the SDS,PSQI,and FertiQoL scale scores of the two groups were re-evaluated,the serum COR concentration was measured,and the satisfaction of the intervention group RIF patients with progressive muscle relaxation training was evaluated.From 28 to 30 days after transplantation,the clinical pregnancy rates of two groups of RIF patients were collected.All data were analyzed by SPSS 21.0 statistical software.Results:After the intervention,a total of 78 RIF patients completed the data collection,including 38 cases in the intervention group and 40 cases in the control group.The results of the study showed that:(1)The general data of the two groups of RIF patients were compared,and the differences were not statistically significant(P>0.05),which was comparable.(2)Comparing the depression of the two groups of RIF patients,there was no significant difference in the SDS score between the two groups before intervention(P>0.05).After the intervention,the SDS score of the intervention group was significantly lower than that of the control group,and the difference was statistically significant(P<0.05).Further comparing the difference between the SDS scores of the two groups of patients before and after intervention,it was still concluded that the reduction in the SDS score of the intervention group before and after intervention was greater than that of the control group,the difference was statistically significant(P<0.05).(3)Comparing the quality of sleep of the two groups of RIF patients,there was no significant difference in the PSQI score before intervention between the two groups of patients(P>0.05).After the intervention,the PSQI score of the intervention group was significantly lower than that of the control group,and the difference was statistically significant(P<0.05).Further comparing the difference between the PSQI scores of the two groups of patients before and after intervention,it was still concluded that the reduction in the PSQI score of the intervention group before and after intervention was greater than that of the control group,the difference was statistically significant(P<0.05).(4)Comparing the quality of reproductive life of the two groups of RIF patients,there was no significant difference in the total scores of FertiQoL,core module scores,and selective treatment module scores between the two groups of patients before intervention(P>0.05).After the intervention,there was no significant difference in the total score of FertiQoL,the core module score and the selective treatment module score between the two groups(P>0.05).Further comparing the difference between the total score of FertiQoL,the core module score and the selective treatment module score before and after intervention between the two groups of patients,which showed that the increase in the total score of FertiQoL and core module score in the intervention group was greater than that in the control group,and the difference was statistically significant(P<0.05).(5)Comparing the serum cortisol concentration between the two groups of RIF patients,the difference in COR concentration after intervention was not statistically significant(P>0.05).Further comparing the difference in COR concentration between the two groups before and after intervention,the difference was still not statistically significant(P>0.05).(6)Comparing the clinical pregnancy rate of the two groups of RIF patients,the clinical pregnancy rate of the intervention group was 65.8%,which was higher than that of the control group at 60.0%,but the difference was not statistically significant(P>0.05).(7)Evaluation of satisfaction of patients in the intervention group with progressive muscle relaxation training.Patients who expressed very satisfaction or satisfaction with the training environment,number of trainings per day,and total training time reached 97.4% to 100%.The overall evaluation of all patients in the intervention group on progressive muscle relaxation training was very satisfactory or satisfactory,with a satisfaction rate of 100%,and 84.2% of patients with RIF indicated that they hope to continue to relax after the transplant.Conclusion:Progressive muscle relaxation training can help relieve depression during the treatment of RIF patients,improve sleep quality,and improve the quality of reproductive life of patients with RIF,does not reduce the Serum cortisol concentration during treatment in patients with RIF,and cannot significantly increase the clinical pregnancy rate of patients with RIF;The intervention method,intervention time and intervention content of this intervention have been recognized by most of the research subjects. |
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