| Objective:Moxibustion was used as an auxiliary treatment and at different times of the acute stage of herpes zoster to treat the elderly herpes zoster(spleen-deficiency and dampness-accumulation type).By observing the short-term and long-term clinical efficacy,it provided a reference for the optimization of moxibustion treatment of herpes zoster in the acute stage and the prevention of post-herpetic neuralgia.Methods:Combined with the distribution of diagnosis and treatment patterns of herpes zoster patients in our hospital and the physiological characteristics of the elderly,it is concluded that the basic pattern of clinical observation of herpes zoster is the syndrome of spleen deficiency and dampness.In this study,108 patients who met the criteria were randomly divided into three groups : control group,experimental group 1 and experimental group 2.The control group received basic treatment(oral valaciclovir sustained release tablets and traditional Chinese medicine treatment).The test group 1 received moxibustion treatment on the basis of the control group(moxibustion should be interventional treatment within 4-5 days of the course of disease).The test group 2 received moxibustion treatment on the basis of the control group(moxibustion should be interventional treatment in 1-3 days).The basic treatment in the three groups was 10 days,and the moxibustion treatment in experimental group 1 and experimental group 2 lasted 14 days.The pain degree and sleep quality were observed after treatment.The incidence of posthpetic neuralgia,the degree of PHN pain and the quality of sleep after 1 month,2 months and 3 months after skin lesions were cured were studied by We Chat,telephone and other return visits.Results:(1)Baseline comparison:Before treatment,baseline analysis was conducted on gender,age,course of disease,location of disease,VAS score and self-rating scale score of sleep status of the three groups of patients.The differences were not statistically significant(p > 0.05),indicating that the three groups were comparable.(2)Visual Analogue ScaleThree groups of subjects one by one on time measurement before and after the treatment,followed up for 1 month,2 months,3 months,a total of five observation point of VAS score,three groups were compared in the five points of VAS score,and in each observation point in time between two groups,the control group,experimental group 1,group 2,from the beginning until the end of the follow-up treatment,three groups of VAS scores are falling,the direction of the three groups respectively before and after treatment compared with statistical significance(p < 0.05);The differences between the control group,experimental group 1 and experimental group 2 were statistically significant(P < 0.05).On the premise of no grouping,the comparison of each observation point was statistically significant(P < 0.05).Pairwise comparison was conducted between the control group,experimental group 1 and experimental group 2.Comparison between the control group and experimental group 1 and experimental group 2 showed statistically significant differences(P < 0.05).Comparison between the control group and experimental group 1 showed no statistically significant differences.(3)Self-rating anxiety scaleThe results indicated that the self-rating scale scores of the control group,experimental group 1 and experimental group 2 all showed a decreasing trend in the five observation points,and the comparison before and after treatment in each group was statistically significant(P < 0.05).The differences between the three groups were statistically significant(P < 0.05).Pairwise comparison was conducted between the control group,experimental group 1 and experimental group 2.Comparison between experimental group 1 and experimental group 2 and control group and experimental group 2 showed statistically significant differences(P < 0.05),while the difference between the control group and experimental group 1 was not statistically significant.(4)The occurrence rate of postherpetic neurlgiaComparing the incidence of sequelae neuralgia in the three groups,p=0.040,the difference was statistically significant(p<0.05),suggesting that the incidence of sequelae in the three groups was different.Conclusion:Moxibustion is effective in the treatment of herpes zoster(syndrome of spleen deficiency and dampness)in the elderly,and the earlier moxibustion is used,the better the effect is in preventing neuralgia after herpes zoster,reducing pain degree and improving sleep quality.This study further optimized the moxibustion treatment of herpes zoster program,safe and effective,easy to operate,has a good clinical application prospect and promotion value. |
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