Clinical Observation On Treatment Of Premature Thelarche (Yin Deficiency And Phlegm-Dampness Syndrome) In Girls

Objective:The effects of the method of nourishing yin and dissolving phlegm and dissolving stagnation on girls with simple breast premature development of yin deficiency and phlegm dampness syndrome were explored and evaluated,and better diagnosis and treatment ideas for this disease were provided and better clinical treatment options were provided.Methods:From January 2018 to January 2019,a total of 64 children who met the pediatrics of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine and met the diagnostic criteria of premature thelarche?yin deficiency and phlegm dampness syndrome?were selected.Divided into two groups.Thirty-two cases were included in the treatment group and 1 case was lost;32 cases were included in the control group and 1 case was excluded;31 cases were finally completed in both groups.The treatment group was given the traditional Chinese medicine decoction Ziyin Huatan Sanjie Recipe,and the control group was given the proprietary Chinese medicine Zhibai Dihuang Wan.The treatment period was 3months.The TCM syndrome scores,maximum length of breast ultrasound,and serum sex hormones LH,FSH,and E₂ levels were recorded before and after treatment,and the results were analyzed using SPSS22.0 statistical software.Finally,the treatment of Ziyin Huatan Sanjie formula was added and subtracted Of early breast development.Results:1.The total effective rate of TCM syndromes in the treatment group was 93.55%and that in the control group was 80.65%.After statistical analysis,P<0.05,the difference was statistically significant,indicating that the treatment regimens of the two groups were effective,and the treatment group was more effective.excellent.2.Comparison of the total scores,main symptoms and comorbidities of TCM syndromes after treatment in two groups,P<0.05,indicating that Ziyin Huatan Sanjie Formula and Zhibai Dihuang Pill are both effective,and the treatment group has a better effect.3.Comparison of the maximum length of breast ultrasound and serum sex hormones FSH and E₂ levels between the two groups of children after treatment,P<0.05,indicating that the treatment group has better efficacy than the control group in reducing the maximum length of breast ultrasound and reducing the levels of serum hormones FSH and E₂.Conclusion:1.The method of nourishing yin and dissolving phlegm and removing sputum is clinically effective in treating girls with premature thelarche;2.The method of nourishing yin and dissolving phlegm and dissolving stagnation to treat premature thelarche has advantages over the control group in the treatment of TCM syndromes;3.The method of nourishing yin and dissolving phlegm and dispersing stagnation is simpler than that of the control group in the treatment of premature thelarche.4.The method of nourishing yin and dissolving phlegm and removing stagnation is simpler than the control group in the treatment of premature thelarche.5.The method of nourishing yin and dissolving phlegm and removing stagnation is simpler than that of the control group in terms of improving breast tissue size and serum FSH and E₂ levels.