| To investigate the colorectal polyps changes in endoscopic,surface mucosa and surrounding mucosa,the location,the size of the diameter,the characteristics of NBI endoscopic,pathological diagnosis,the distribution of gender and age in the population,and the characteristics of early cancer Analyze the relationship between them,summarize the characteristics of endoscopic colorectal polyps and the risk factors for early canceration,and provide a theoretical basis for the early diagnosis and treatment of endoscopic colorectal cancer.Methods: From January 2018 to January 2020,800 cases of colorectal polyps were extracCperative pathological data.Among them,173 cases were diagnosed with early carcinogenesis,201 polyps were diagnosed with early carcinogenesis,and 140 patients with clear endoscopic and pathological data were treated with NBI technique.Gender and age of polyp patients,morphology of endoscopic lesions,surface mucosa,size,location of onset,characteristics of NBI techniques,type of pathological diagnosis,There is no statistical analysis of early carcinogenesis.Use X2 test or Fisher’s exact test to analyze the related risk factors of early cancer development through logistic univariate and multivariate regression models and the SPSS26.0 was used for statistical analysis,p<0.05 was statistically significant.Results: 1.characteristics and risk of early carcinogenesis:1.1 Diameter: 1160(81.4%)with a diameter ≤ 1cm;128 polyp s(9.6%)with a diameter between 1.1-1.9.136(10%)are ≥ 2cm in diameter.Among the cancerous polyps,there are 65 polyps with a diameter of 1 cm or less,51 polyps with a diameter of 1.1-1.9,a nd 77 polyps with a diameter of 2 cm or more.1.2 Form: 832(58%)broad-based type,304(22%)sub-type an d 288(20%)pedicle type.The pathological types of various polyps are mainly tubular adenoma.Among them,there are 93 pedicles,52 pedicles and 56 broad-based ones.1.3 Surface changes: 988(69%)smooth type,280(20%)rough,156(11%)lobulated,common pathological types of different surfa ce mucosa are different,including villous glands The surface mucos a of the tumor is often lobulated.Among the cancerous polyps,78 were smooth,46 were rough,and 77 were lobulated.1.4 Peripheral mucosa: 21(1.5%)with leukoplakia,1403(98.5%)without leukoplakia,and the pathological type in leukoplakia po lyps is often adenomatous polyps.Among the cancerous polyps,11 had white spots,and 10 had no white spots.1.5 NBI endoscopy: Of the 140 polyps observed with NBI end oscopy,83 were adenomatous polyps and 57 were non-adenomatous polyps.The sensitivity in distinguishing benign from malignant poly ps is 92.9%,specificity 89.1%,positive predictive value 85.2%,neg ative predictive value 93%,and accuracy 90.0%.1.6 Location: The incidence of polyps in the left colon is 712(50%),the incidence of polyps in the right colon is 472(33%),the r ectum is 240(17%).There are 104 left colon and 24 rectum2.Pat hological features: Tubular adenoma was 584(41%),tubular-villo us adenoma was392(28%),inflammatory polyp was 288(20%),hyperp lasticpolypwas144(10%),villous gland At least 16 tumors(1%).The pathological diagnosis indicated canceration: 9 villous adenoma(56%),88 villous tubular(22%),and 104(17%)tubular adenoma.2.C ancer Related Factors 3.Gender and age:There were 453 males(56.6%)and 347 females(43.4%)with a sex ratio of 1.3: 1.The average age of the patient population is 60 years,the minimum age is 28 years,and the maximum age is 84 years.Among them,320 patients(40%)were ≥60 years old,318 patients(39.8%)were between 45 and 59 years old,and 162(20.3%)were ≤44 years old.In the distribution of different genders and different ages,the number of males ≥60 years old was at most 228(28.5%).The majority of cancerous patients are males;the older the age,the higher the rate of canceration.Males and patients ≥60 years old have the most,83 cases,accounting for 48.0%.Conclusion:1.Endoscopic polyp diameter ≥ 2cm,pedicle-shaped,lobulated,with leukoplakia changes are prone to early cancer,lobulated is an independent risk factor for early polyps of polyps;2.NICE classification under NBI endoscopy has a high diagnostic value for the judgment of benign and malignant polyps;3.colorectal polyps occur on the left In the semicolon,the risk of canceration is positively correlated with age and not with gender;... |
