| Objective: To explore the clinical characteristics of infant intracranial hemorrhage in Tibet,in order to better guide the clinical diagnosis and treatment,through the analysis of AEEG and prognosis of infant intracranial hemorrhage,so as to predict the prognosis of infant.The clinical data of 83 children with intracranial hemorrhage who were hospitalized in pediatrics department of the people's Hospital of Tibet Autonomous Region from January 2016 to December 2019 were analyzed retrospectively.From June 2018 to December 2019,a total of40 children hospitalized in the people's Hospital of Tibet Autonomous Region due to intracranial hemorrhage were examined for AEEG,with the exception of a large number of false errors,3 cases could not be interpreted,3 cases died after discharge,4 cases lost contact during follow-up,a total of 30 cases,and the 30 children were followed up after discharge.At the same time,30 cases of AEEG were collected from the patients who were hospitalized in the people's Hospital of Tibet Autonomous Region.Results: 83 patients with intracranial hemorrhage were diagnosed and treated in 4 years,including 56 males and 27 females,the ratio of males to females was 2:1 30 minutes to 12 months,average 1.2months;44 cases(53.0%)were less than 1 month,39 cases(47.0%)were between 1 month and 12 months;etiology: late vitamin K-dependent factor deficiency was the most common in 36 cases(43.4%),newborn hypoxic-ischemic encephalopathy in 29 cases(34.9%),multiple organ dysfunction in 2 cases(2.4%),thrombocytopenia in 3 cases(3.6%),unknown etiology in 13 cases(15.7%);age distribution: < 1 month 44 Cases(53.0%),39 cases(47.0%)from January to December;in regional distribution: 14 cases(16.8%)in Lhasa(5 cases in Lhasa,9 cases in other areas of Lhasa),33 cases(39.7%)in Naqu area,14 cases(16.8%)in Shannan area,13 cases(15.8%)in Shigatse,4 cases(4.8%)in Linzhi Area,4 cases(4.8%)in Changdu area and 1 case(1.3%)in Ali area;clinical manifestations: 45 of 83 patients(54.2%)were non-specific Only 37 patients(44.5%)had specific manifestations of nervous system,1 patient(1.3%)had both specific and non-specific manifestations of nervous system;40 children hospitalized in the people's Hospital of Tibet Autonomous Region from June 2018 to December 2019 were followed up for 1-3 months.There were 6 cases lost contact,4 cases died within 1 day after discharge,10 cases had a good prognosis,20 cases had a bad prognosis.The results of prognosis among children with different grades of AEEG in the intracranial hemorrhage group showed that the poor prognosis rate of children with normal,mild and severe abnormalities were 25.0%,60.0% and 90.0%,respectively.The difference was statistically significant by x2 test.Conclusion: the incidence rate of intracranial hemorrhage in infants is higher: the higher the altitude,the higher the incidence;the intracranial hemorrhage of infants lacks specific clinical manifestations.When the infants suffer from poor feeding,poor reaction,full front fontanelle and pale facial complexion,we should be alert to the intracranial hemorrhage of children.Late vitamin K deficiency is still a major cause of intracranial hemorrhage in Tibet.In some parts of Tibet,vitamin K injection at birth has not become a routine.Therefore,we should strengthen the training of medical staff,improve the injection rate of vitamin K at birth,and reduce intracranial hemorrhage caused by vitamin K deficiency.The results of AEEG showed that the more serious the AEEG result was,the worse the prognosis was;therefore,the children with intracranial hemorrhage should be treated actively to reduce the remaining neurological sequelae as much as possible. |
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