Control Study Of The Effect Of Early Intervention On Physical Development And Neurosychological Development Of Preterm Infants

Objective:To collect and analyze the weight,length and neuropsychological development evaluation results of preterm infants,and to explore the effect of early intervention on physical development and neuropsychological development of preterm infants,and to analyze the relevant factors for neuropsychological development.Methods:106 preterm infants visting the Child Health Care in the First Hospital Lanzhou University were classified into intervention group(n=54)and control group(n = 52)according to early intervention(exercise,language,cognition,emotional communication,social interaction ability training).The weight and body length were measured at the corrected age of 3 months and 6 months.The 20 items neuromotor assessmentent was used to assess the neurological development at the corrected age of2 months,3 months and 4 months.The developmental quotient scores were assessed by the Gesell Developmental Scale at the corrected age of 6 months and 12 months.To explore influencing factors of neuropsychological development at the corrected age of 6 months.Results:1.Among the clinical datas,birth weihgt,gestational age,gender,perinatal complications,education background of caregivers,monthly household income,neonatal pneumonia,neonatal hyperbilirubinemia,anemia,neonatal hypoglycemia,bronchopulmonary dysplasia,neonatal respiratory distress syndrome,asphyxia of newborn,hypoxic-ischemic encephalopathy,intracranial hemorrhage in two groups had no significant difference(P>0.05).2.At the corrected age of 3 months and 6 months,The weight,bodylength,the Z-scores of weight-for-age and Z-scores of body length-for-age of preterm infants in the control group were higher than those in the intervention group,and the differences were statistically significant(P<0.05).3.The 20 items neuromotor assessmentent was used to assess the neurological development at the corrected age of 2 months,3 months and 4 months.The intervention group had a higher constituent ratio than the control group,and the differences were statistically significant(P<0.05).4.At the corrected age of 6 months and 12 months,The intervention group had a higher developmental quotient scores on five Gesell subscales than the control group,and the differences were statistically significant(P<0.05).5.At the corrected age of 6 months,The developmental quotient scores on Gesell subscales were positively correlated with gestational age and education background of caregivers,and the differences were statistically significant(P<0.05).Conclusion:1.The youngerthe gestational age,and the relatively backward neuropsychological development.2.Nutrition and feeding guidance could impove the physical development of preterm infants.3.Enhanced training and abnormal posture intervention could impove the neuropsychological development of preterm infants,which is worth generalization.4.With higher education could promote the neuropsychological development of preterm infants.