Clinical And Pathological Feature Of 1209 Patients With Gastric Polyps

ObjectiveThis study discussed the clinical and pathological feature of 1209 patients with gastric polyps(GP)in the first hospital of Lanzhou University.To provide theoretical basis for prevention andearly diagnosis and treatment of GP.MethodsThis study included 1209 clinical records of GP patients from the first hospital of Lanzhou University from January 2007 to August 2019.To descriptive analyse the composition of these patient's basic information,gastroscopy,biopsy,Helicobacter Pylori(H.pylori)testing,accompanying disease,treatment and to compare whether there were statistical differences in different years,different age groups and different pathological types.Results1.GP patients were mostly female(60.6%),with an average age of 54.4 years,mainly from Lanzhou City,Tianshui City and Baiyin City(63.3%),most of them were Han nationality(96.1%)and married patients(96.9%);In terms of occupational distribution,farmers and liberal professions predominate(52.6%);85.6% of patients denied smoking,84.1% denied drinking and 3.3% had a family history of digestive tract tumors;The main clinical manifestations were abdominal pain and abdominal distension(81.0%);78.8% of patients with gastritis;In terms of polyp features,polyps were mainly single(62.7%),diameter ? 5mm(53.8%),distributed in antrum/pyloric/gastric angle(32.1%)and Yamada II and III(65.0%);In terms of pathological classification,76.6%were hyperplastic polyps(HPs);H pylori positive rate was 62.1%,and there was no significant difference in the influence of various detection methods on the results;Most patients underwent endoscopic polyposis resection(91.1%).2.As time goes on,the number of GP patients showed a significant upward trend.In terms of demographic characteristics,the proportion of men in the sex has declined,the proportion of people living in Lanzhou increased,the proportion of unmarried people in marriage increased,the proportion of farmers and staff in occupation decreased,the proportion of smoking and drinking decreased and the proportion of asymptomatic patients in symptoms increased;Under gastroscopy,the proportion of patients with gastritis increased,the proportion of patients with duodenalitis decreased,the proportion of single polyp patients decreased,the proportion of polyp located in antrum/pyloric/gastric angle decreased,the proportion of polyp located in cardia/fundus increased,the proportion of polyp with maximum diameter?5mm increased,the proportion of Yamada I increased,and the proportion of Yamada ? decreased;In terms of pathological classification and H pylori infection rates,the proportion of HPs decreased,while the proportion of fundus gland polyps(FGP)and adenomatous polyps(APs)increased,H.pylori infection rate decreased;In terms of associated diseases,the proportion of cholecystitis,fatty liver,hyperlipidemia and arrhythmia increased;In terms of treatment,the proportion of argon plasma coagulation(APC)decreased,and the proportion of endoscopic mucosal resection(EMR)and endoscopic submucosal dissection(ESD)increased.3.Among different age groups,in terms of body mass index(BMI),patients aged less than 30 years(92%)and those aged over 79 years(88.9%)were mainly underweight and normal,while those aged between 30 and 69 years were normal and overweight(79.1%);Under gastroscopy,duodenal ulcer was more likely to occur in patients aged 30-69(90.5%),gastric ulcer(96.8%)and CAG(94.7%)were more likely to occur in patients over 40 years of age,and patients aged 40-69 were more likely to have single polyps(78.8%);In terms of associated diseases,patients over 40 years of age are more likely to be associated with cholecystitis,hypertension,diabetes,arteriosclerosis,coronarg atherosclerotic cardiopathy(coronarg heart disease),gallstone and arrhythmia;In terms of treatment,patients aged 10-19 years were treated with EMR,patients over 80 years of age were treated only with simple medication,APC and surgery,and patients of the rest of the age groups were mainly treated with APC?EMR and multiple methods.4.Compared with non-FGP patients,FGP patients had more asymptomatic and GERD,polyps are small and multiple,with fewer smokers and gastritis patients,polyps are less located in the antrum/pyloric/gastric angle,with lower atypical hyperplasia and H.pylori infection rates.Compared with non-HPs patients,HPs patients had more bile regurgitation patients,polyps are smaller in size and more likely to located in the corpora ventriculi and be Yamada ? and ?,more patients were treated with simple medication and APC,with fewer GERD patients and lower atypical hyperplasia and IM rates.Compared with non-APs patients,APs patients had more farmers,but fewer students and staff,more smoker and drinker,more patients with gastritis and fatty liver,polyps are mostly single,large and located in antrum/pyloric/gastric horn,Yamada ? and ?,accompanied by higher atypical hyperplasia and IM rate.ConclusionGP patients were mainly middle-aged women,most with gastritis(78.8%),the H.pylori infection rate is 62.1%.Most of the GP were single(62.7%),mainly located in antrum and multiple parts,with a diameter?5mm(53.8%),and HPs(76.6%)is the main GP of patients.As time goes on,the number of GP patients showed a significant upward trend,the detection rate of small and flat polyps increased,the proportion of HPs decreased while the proportion of FGP increased,and the H.pylori infection rate decreased.FGP is small and multiple with lower atypical hyperplasia and H.pylori infection.APs is large and single,with higher atypical hyperplasia and IM rate.