Multimodal CT Based Study Of Correlative Factors Of Collateral Circulation And Prognosis In Patients With Acute Anterior Circulation Cerebral Infarction

Objective:Use multimodal CT to study the factors related to collateral circulation status and prognosis in patients with acute anterior circulation cerebral infarction,and to explore the relationship between the formation of collateral circulation and the patient's prognosis,and to provide a basis for individualized treatment plans for patients to achieve the best prognosis.Methods:Patients with acute anterior circulation cerebral infarction who were hospitalized in the Department of Neurology,First Affiliated Hospital of Suzhou University from October 2018 to December 2019 were collected,and the patients were grouped according to the quality of the collateral circulation and prognosis,and the various groups were compared Clinical and laboratory data were used to determine the influential factors of collateral circulation and prognosis in patients,and to explore the relationship between collateral circulation and patient prognosis.The data were analyzed by SPSS 20.0 statistical software,and the difference was considered statistically significant at p<0.05.Results:Among the 173 patients with acute anterior circulation cerebral infarction finally included,111 were male(64.2%)and 62 were female(35,8%),with an average age of 64.12 ± 13.556 years.Among them,120 had good collateral circulation(69.4%),and 53 had poor collateral circulation(30.6%).103 patients with good prognosis(59.5%)and 70 patients with poor prognosis(40.5%).1.Univariate analysis showed age,history of diabetes,history of atrial fibrillation,responsible blood vessels,large vessel occlusion or severe stenosis,ischemic hypoperfusion volume,core infarct volume,baseline NIHSS score,ASPECT score in the good collateral circulation group and collateral circulation The distribution of the bad group was statistically significant(p<0.05),Further multivariate analysis suggested that ASPECT score and ischemic hypoperfusion volume were related to collateral circulation.2.The distribution of cardiogenic embolism and small arterial occlusion cerebral infarction was statistically significant in the good collateral circulation group and the poor collateral circulation group(p<0.05).3.Univariate analysis showed age,previous atrial fibrillation history,intravenous thrombolytic therapy,post-infarction bleeding,large vessel occlusion or stricture,fasting blood glucose,high-density cholesterol,homocysteine,baseline NIHSS score,ASPECT score,and rLMC The distribution of the scores in the good prognosis and the poor prognosis groups was statistically significant(p<0.05).Multivariate analysis suggested that the NIHSS score,HDL,fasting blood glucose,ASPECT score,and intravenous thrombolysis were related to short-term functional prognosis.4.The distribution of rLMC scores in the good prognosis and poor prognosis groups was statistically significant(p<0.05),and patients in the good prognosis group had higher rLMC scores.Conclusions:1.ASPECT score and ischemic hypoperfusion volume are related to collateral circulation.2.The prognosis of patients with low NIHSS score,high ASPECT score,low fasting blood glucose and intravenous thrombolysis therapy.3.Baseline NIHSS score?6.5 and baseline ASPECT score<8.5 indicate poor prognosis.