Study On The Correlation Between Different Constitution Of Traditional Chinese Medicine And AMH Level And Influencing Factors In PCOS Patients

Objective: This subject explores the characteristics of anti-Müllerian hormone(AMH)in patients with polycystic ovary syndrome(PCOS)and the distribution law of TCM constitution,and influencing factors of this disease.Explore the distribution of AMH in PCOS of different constitutions.To further analyze the differences and correlations between the AMH value and different types of TCM constitutions of PCOS patients,with clinical indicators and influencing factors.It aims to provide new ideas for the diagnosis and treatment of PCOS clinically.Methods: A total of 226 cases that met the inclusion criteria were collected from the gynecology clinic and inpatient department of gynecology clinic and gynecology inpatient department of Yunnan Traditional Chinese Medicine Hospital.Organize patient data through questionnaire survey,use SPSS software to statistically analyze the correlation between AMH level of all cases and TCM constitution,clinical indicators,and influencing factors,as well as the correlation of PCOS patients' TCM constitution and influencing factors.Result1.The age range of 226 PCOS patients is 18-38 years old,with an average age of 23.5years.The patients are mainly distributed between 20-30 years old,of which the proportion of 21-25 years old is the highest(46%),and the proportion of patients over30 years old is the lowest(4.9%);AMH values range from 3.59 ng / ml to 15.61 ng /ml,with an average value of 6.785 ng / ml.Among them,the level of AMH is mainly concentrated in 3.59-6.50 ng / ml,accounting for 51.8%;there is no statistically significant difference between AMH and age,P> 0.05;2.Occupational bias of 226 patients is mainly based on mental power,accounting for62.8%;the course of disease is mainly concentrated in 5 years or less,accounting for71.7% of the total number.3.The number of patients with hyperandrogenism is as high as 63.7%,LH / FSH?2patients 50.0%,acne patients 59.7%,and hairy patients 29.6%;BMI?23 is 153,accounting for 67.7% of the total;WHR?There are 118 patients with 0.85,accounting for 52.2% of the total number.AMH was positively correlated with TESTO,LH,acne score and hirsutism score,the difference was statistically significant,P <0.05;AMH was not statistically different from BMI,WHR,P> 0.05.4.The arrangement of AMH values in each TCM constitution type is as follows:blood stasis quality>damp heat quality>phlegm and dampness quality>special quality> yin deficiency quality>yang deficiency quality>peace quality> Qi depression quality>Qi deficiency quality;blood stasis The AMH value of quality was significantly higher than other constitutions,and the AMH value of damp heat quality and phlegm-humidity was significantly higher than that of Yin deficiency,Yang deficiency,Qi depression and Qi deficiency,the difference was statistically significant,P <0.05.There was no statistically significant difference between the other groups,P>0.05.5.The distribution of physical types of PCOS patients is as follows: phlegm and dampness(46,20.4%)>damp heat quality(33,14.6%)>blood stasis quality(30,13.3%)> Qi stagnation(28,12.4)%)= Yang deficiency quality(28,12.4%)> Peaceful quality(23,10.2%)> in deficiency quality(20,8.8%)> Qi deficiency quality(15,6.6%)> Special quality(3,1.3%).6.Phlegm and dampness: WHR and phlegm and dampness are positively correlated(P=0.032),BMI and phlegm and dampness are positively correlated(P=0.027),greasy diet and phlegm and dampness are positively correlated(P=0.003),sweets and phlegm are The quality was positively correlated(P=0.002),and the number of weekly exercises was negatively correlated with phlegm and dampness(P=0.000).7.Damp-heat quality: TESTO is positively correlated with damp-heat quality(P =0.045);acne degree is positively correlated with damp-heat quality(P=0.001);drinking history is positively correlated with damp-heat quality(P=0.024);preserved food is correlated with damp-heat quality Negative correlation(P=0.000);greasy diet was positively correlated with moist heat(P=0.007).8.Blood stasis quality: AMH level is positively correlated with blood stasis quality(P=0.000);acne degree is negatively correlated with blood stasis quality(P=0.026);pickled diet is positively correlated with blood stasis quality(P=0.01).9.Qi depression: E2 level is positively correlated with Qi depression(P=0.029);AMH level is negatively correlated with Qi depression(P=0.001);Mental stress is positively correlated with Qi depression(P=0.000);The nighttime sleep time was negatively correlated with qi depression(P=0.02).10.Yang deficiency: FSH level is negatively correlated with Yang deficiency(P=0.007);acne degree is negatively correlated with Yang deficiency(P=0.013);drinking history is negatively correlated with Yang deficiency(P=0.006);Greasy diet was negatively correlated with yang deficiency(P=0.008);birth weight was positively correlated with yang deficiency(P=0.017).11.Peaceful quality: There was a negative correlation between salted food and Peaceful quality(P= 0.028),and there was a positive correlation between exercise times per week and Peaceful quality(P = 0.034).12.Yin Deficiency Constitution: E2 level was negatively correlated with Yin Deficiency Constitution(P= 0.000),raw and cold diet was positively correlated with Yin Deficiency Constitution(P = 0.045),stress degree was negatively correlated with Yin Deficiency Constitution(P= 0.014),birth weight was negatively correlated with Yin deficiency constitution(P=0.016).13.Qi deficiency: patients with Qi deficiency have low BMI(P=0.028);patients with PCOS with deficiency of Qi have low AMH(P=0.003).Conclusions: 1.The AMH value of PCOS patients is higher than that of women of healthy childbearing age,and it is positively correlated with LH,TESTO,acne,and hairiness;2.The blood stasis quality of PCOS patients is significantly higher than other constitutions;phlegm dampness,damp heat AMH The level was significantly higher than that of Qi deficiency,Yang deficiency,Qi depression,and Yin deficiency.3.The traditional Chinese medicine constitutions of PCOS patients are mainly phlegm and dampness,dampness and heat,and blood stasis.4.The main risk factors for phlegm and dampness are BMI,WHR,sweets,and greasy diet,and the protective factors are the number of exercises per week;the main risk factors for dampness and heat are TESTO,acne,drinking,and greasy diet,and the protective factors are pickled diet;blood stasis Qualitative risk factors include AMH,pickled diet,and acne in patients with blood stasis.