Study On The Distribution Features Of TCM Syndrome Elements Of Helicobacter Pylori Associated Chronic Gastritis

Objective:Through researching and analyzing the clinical investigation data of patients with Helicobacter pylori(Hp)associated chronic gastritis,to summarize disease relative factors,the distribution of patient’s condition and TCM syndromes,which hoping to provide a scientific theoretical basis for the TCM dialectical treatment of Hp associated chronic gastritis.Methods:Collecting 300 cases of patient with Hp associated chronic gastritis in accordance with diagnostic criteria as research objects,collected and organized relevant clinical data and information,established a database,used the SPSS 25.0 software for statistical analysis to summarize and analyze its distribution regularity of TCM syndrome elements and state of disease.Results:1.Among the 300 patients with Hp associated chronic gastritis,142 were men and 158 were women,the men to women ratio was 0.9:1,and women were more than men.For age,the majority were middle-aged and elderly patients.2.In these collected cases,180 cases of patient had bad dietary preferences and tobacco and alcohol habits.Among them,smokers appeared the most frequent,accounting for 32.67%,followed by those who like strong tea,coffee,chocolate,and those who like to eat these foods of spicy stimulation,pickled smoked,cold and rough,and drinkers.There were 213 cases of eating out,the most was frequently eating out,accounting for 40.33%,followed by occasional eating out(34.00%),and never eating out was the least(25.67%).3.Among these researched cases,the most common symptom of spleen and stomach was bloating,the most common symptom was thin sloppy stool,the most proportion of oral symptom was bitter mouth,the highest proportion of tongue was red tongue,and mainly consists of tongue fur were thin yellow fur,thin white fur and greasy fur.159 cases were chronic superficial gastritis(CSG),accounting for 53.00%,mainly moderate CSG;141 cases were chronic atrophic gastritis(CAG),accounting for 47.00%,mainly mild CAG.The lesion under gastroscope mainly was gastric antrum,accounting for 94.33%,followed by gastric angle and gastric body.The inflammation of the gastric mucosal surface under the endoscope mainly was the manifestation of erosion,accounting for 55.67%,followed by rough,hyperemia and exudation,and erythema.4.In these collected cases,266 patients could be extracted the disease location syndrome.Counting a frequency distribution ratio>2%of the disease syndromes,the main syndrome elements of disease location were stomach(88.72%),spleen(19.17%),and liver(5.26%).Observing the combination of syndrome elements found that the single disease location was the most(84.96%),the double syndrome’s elements was the second(13.54%),and the three-position was the least(1.50%).In the combination of disease location,the most was stomach,followed by stomach and spleen,spleen,stomach and liver.261 patients could be extracted the disease nature syndrome.Counting a frequency distribution ratio ≥2%of the disease syndromes,the main syndrome elements of disease nature were found to have Qi stagnation(53.69%),Qi deficiency(23.15%),Yin deficiency(18.92%),dampness(13.79%),Yang deficiency(12.81%),heat(6.40%).Observing the combination of syndromes elements found that the single disease nature was the most,accounting for 71.92%,double syndrome’s elements of disease nature was 24.63%,triple disease and above were 3.45%.In the combination of syndrome’s element of disease nature,the most was Qi stagnation,followed by Yin deficiency,Qi deficiency and Yang deficiency,Qi deficiency,dampness,Qi stagnation and dampness,heat,Qi deficiency and Qi stagnation,Qi stagnation and Yin deficiency.There were 116 cases(57.15%)with excess syndrome,21 cases(10.34%)with mixture of excess and weak syndrome,and 66 cases(32.51%)with weak syndrome.5.The research shows the distribution of syndromes elements of disease location of Hp associated chronic gastritis had correlation with gastritis type and the inflammation of the gastric mucosal surface under the endoscope,while the distribution of syndromes elements of disease nature of Hp associated chronic gastritis had no correlation with gastritis type and the inflammation of the gastric mucosal surface under the endoscope.The distribution of syndromes elements of Hp associated chronic gastritis had no correlation with patient’s gender,age,lesion location,and histopathological changes.Conclusion:1.The research shows the predilection age of this disease is 51-60 years,with more women than men.Patients with bad habits of smoking,eating strong tea,coffee,chocolate the food of spicy stimulation,and frequently eating out are closely related to the occurrence of this disease.2.This disease had mainly symptoms such as stomach bloating,thin sloppy stool,bitter mouth,red tongue,thin yellow fur.Most gastritis types were moderate chronic superficial gastritis and mild chronic atrophic gastritis.The lesion under gastroscope was mainly in the gastric antrum,and the inflammation of the gastric mucosal surface under endoscope was manifested by erosion.3.The main syndrome elements of disease location of this disease were stomach,spleen,and liver,the combination of syndromes elements was dominated by single disease location,the combination of disease location most was stomach,followed by stomach and spleen,spleen,and stomach and liver.The main syndrome elements of disease nature had Qi stagnation,Qi deficiency,Yin deficiency,dampness,Yang deficiency,heat,the combination of syndromes was dominated by single disease nature,the combination of syndrome’s element of disease nature most was Qi stagnation,and excess syndrome was more than weak syndrome and mixture of excess and weak syndrome.4.The distribution of syndromes elements of disease location of this disease had correlation with gastritis type and the inflammation of the gastric mucosal surface under the endoscope,while the distribution of syndromes elements of disease nature of this disease had no correlation with gastritis type and the inflammation of the gastric mucosal surface under the endoscope.The distribution of syndromes elements of this disease had no correlation with patient’s gender,age,lesion location,and histopathological changes.