| Purposes:To explore the effect of intestinal adhesion relieving decoction on the treatment of postoperative adhesive intestinal obstruction.Based on the analysis of the pharmacological effects of the prescription and its mechanism of action,compare,analyze and evaluate the advantages and feasibility of traditional Chinese medicine enema combined with Western medicine for postoperative adhesive intestinal obstruction,providing new ideas for the clinical treatment of postoperative adhesive intestinal obstruction.Methods:Using the method of random control,a total of 30 patients were included in the experiment.According to the condition,a total of 15 patients in the control group and 2 patients were lost.There were 15 persons in the experimental group,and 1 person fell off.A total of 3 people fell off.Control group:conventional Western medicine treatment,fasting and water-relief,gastrointestinal decompression,acid suppression and vomiting,somatostatin,antibioties,parenteral nutrition support.Treatment group:In addition to basic treatment in the control group,Chinese medicine ChangNianLianHuanJie Tang was added.Take one dose daily and measure C-reactive protein?CRP?,interleukin-6?IL-6?,Prothrombin time?PT?,activated partial coagulation activity at D1,D7,and D14.The content of factors such as enzyme time?APTT?,thrombin time?TT?,fibrinogen?FIB?,and D-dimer?DD?were evaluated by pain,GSRS,and KPS scores.Results:Aeeording to statistical analysis,the basic conditions of the two groups of subjects were comparable before treatment?P>0.05?.1.Pain:There was no significant difference in pain before treatment between the two groups of patients?P>005?,which is comparable.There was statistical difference between the two groups after treatment?P<0.05?,which was statistically significant.2.Serun inflammatory factors CRP,IL-6:There was no significant difference in serum inflammatory factors before treatment between the two groups of patients?P>0.05?,and they were comparable.Comparing within the group,the levels of CRP,IL-6,in the two groups decreased after treatment?P<0.05?,which was statistically significant;comparison between groups,the levels of CRP,IL-6,in the experimental group.The decline was significantly better than that of the control group?P>0.05?,which was statistically significant.3.GSRS score:There was no statistical difference in gastrointestinal symptoms score between the two groups of subjects before treatment?P>0.05?,which is comparable.There was an interaction between time and treatment.The gastrointestinal symptom scores of the two groups of patients decreased?P<0.05?,and the experimental group was better than the control group with a statistical difference?P<0.05?.4.Serun coagulation factor indicators:There were no significant differences in the coagulation factors before treatment between the two groups of patients?P>0.05?,which are comparable.Comparing within the group,the levels of coagulation factors in the two groups had no significant changes after treatment,which was not statistically significant?P>0.05?,Comparing between groups,the decline in coagulation factor levels in the experimental group was not significantly different from that in the control group.Statistical significance?P>0.05?.5.KPS score:The KPS scores before treatment of the two groups were not significantly different?P>0.05?,and were comparable.Within the group,the KPS scores of the two groups increased after treatment?P<0.05?,statistically significant;compared between groups,the increase in the KPS score of the experimental group was significantly better than that of the control group?P<0.05?,with Statistical significance.Conclusions:ChangNianLianHuanJie Tang enema combined with Western medicine has obvious advantages in clinical treatment of postoperative adhesive intestinal obstruction,which can obviously relieve patients' symptoms such as nausea and vomiting,abdominal distension and abdominal pain,reduce patients1 serum inflammatory factor indicators,and shorten the course of the disease. |
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