The Effect Of Pulmonary Hypertension On The Prognosis Of Patients With Left Heart Failure

Objectives:The purpose of this study was to investigate the effects of pulmonary hypertension(PH)on the prognosis of patients with left heart failure.Method:A total of457 patients with left heart failure admitted to the first affiliated hospital of xinjiang medical university from January 2017 to December 2017 were included and followed up until January 2019.According to the level of pulmonary artery pressure,they were divided into 204 cases of normal pulmonary artery pressure heart failure group,(PASP<35mmHg)and 253 cases of pulmonary hypertension and heart failure group(PASP≥35mmHg),follow-up and January 2019,the finish event as follows:The effects of pulmonary hypertension on the prognosis of patients with left heart failure were analyzed.Results:A total of 457 patients with left heart failure were included in this study,with a mean follow-up of 9.32±5.21 months.The length of hospital stay in the group with heart failure and pulmonary hypertension was significantly higher than that in the group with normal pulmonary hypertension(P<0.05).Readmission rate(112 44.3%vs 71 34.8%,P<0.05)and mortality rate(30 11.9%vs 11 5.4%,P<0.05)were higher in the heart failure group with pulmonary hypertension than in the normal group,with statistically significant differences..Kaplan-meier analysis showed that there was a statistically significant difference in the prognosis between the heart failure group with pulmonary hypertension and the normal pulmonary hypertension group(?~2=12.852,p<0.001),and the prognosis of the normal pulmonary hypertension group with heart failure was significantly better than that of the heart failure group with pulmonary hypertension.Univariate and multivariate cox regression analysis showed that pulmonary artery pressure(HR=1.367,95%HR 1.019-1.833,P=0.037),creatinine(HR=1.006,95%HR1.001-1.011,P=0.043),age(HR=1.019,95%HR 1.006-1.032,P=0.004)had an impact on the prognosis of the patients,with statistically significant differences and independent risk factors.Conclusion:Pulmonary artery pressure plays an important role in predicting the prognosis of patients with left heart failure.