Correlation Between Blood Supply Of Subchondral Bone And Osteoarthritis In Knee Joint

Objective: To investigate the correlation between the blood supply to subchondral bone and osteoarthritis of knee joint by medical imaging,so as to reveal the role of the blood supply to subchondral bone in the occurrence and development of osteoarthritis of knee joint.Methods: Eighty patients with diagnosed osteoarthritis of knee joint were selected.According to the Kellgren-Lawrence grade(K-L score),the patients were divided into group I-IV,with 20 patients per group.Additionally,10 healthy individuals were selected as healthy group.All the patients were examined the same 64-slice spiral CT angiography(CTA)in lower extremity artery.Four rectangular subchondral bones with the same size(15 mm × 20 mm)were selected from medial and lateral distal femur and proximal tibia at the axial position as regions of interest(ROIs).CT values in ROIs before and after enhancement were measured,and enhancement rate was calculated.Results: The enhancement rate in ROIs of medial and lateral distal femur and proximal tibia showed significant differences among the 5 groups(P < 0.05).With the aggravation of osteoarthritis of knee joint,the enhancement rate increased significantly.Conclusion:With the aggravation of osteoarthritis of knee joint,the blood supply to subchondral bone increased.