| Background:Hepatocellular carcinoma is one of the most common malignant tumors in China.Its morbidity ranks fourth in malignant tumors,and its mortality rate ranks second in malignant tumors.For the treatment of hepatocellular carcinoma,liver resection is the main method.With the continuous progress of medical treatment methods,a new treatment method hasemerged in recent years,namely radiofrequency ablation assisted liver resection.This technique can reduce the recurrence rate and reduce the bleeding by sealing the surrounding pipes of tumor tissues with heat energy and ablating the lesions.By comparing the methods of conventional liver resection and radiofrequency ablation assisted liver resection,this paper summarizes a more suitable surgical method for patients.Objective:To analyze the effect of radiofrequency ablation assisted liver resection for hepatocellular carcinoma.Methods:The clinical data of 173 hepatocellular carcinoma patients with clinical stage Ia,Ib,IIa who accepted surgical resection in the First Affiliated Hospital of Zhengzhou University from June 2016 to December 2019 were retrospectively analyzed.Eighty-two patients underwent RFA-LR(the RFA-LR group,n=82),and 91 patients underwent conventional liver resection(the LR group,n=91).The comparison of two groups after treatment in patients with the intraoperative blood loss,operation time,intraoperative blood transfusion,hepatic hilar occlusion time,serum indexes of liver function(AST、ALT、TBil、PT、ALB)in the first and four day after operation,postoperative complications,the length of days in hospital and hospitalization expenses,median tumor-free survival time.Results:1.The intraoperative blood loss of the RFA-LR group was 265.00±277.32 m L,and the intraoperative blood loss of the LR group was 505.49 ±488.90 m L.The difference was statistically significant(P<0.05).2.The operation time of the RFA-LR group was 145.24±58.01 min,and the operation time of the LR group was 168.00±57.72 min.The difference was statistically significant(P<0.05).3.The hepatic hilar occlusion time of the RFA-LR group was 8.13±8.75 min,and the hepatic hilar occlusion time of the LR group was 14.27±13.55 min.The difference was statistically significant(P<0.05).4.The postoperative complications(Liver failure,bile leakage,massive ascites,postoperative bleeding)rate of the RFA-LR group was 7.32 %,and the postoperative complications(Liver failure,bile leakage,massive ascites,postoperative bleeding)rate of the LR group was 21.33 %.The difference was statistically significant(P<0.05).5.The hospitalization expenses of the RFA-LR group was 64474.56±11294.15 yuan,and the hospitalization expenses of the LR group was 59883.12±15426.13 yuan.The difference was statistically significant(P<0.05).6.The tumor free survival rateand of the RFA-LR group at 12,24 and 36 months after surgery was 83.5%、63.7%、39.7%,and the median tumor-free survival time ofthe RFA-LR group was 28.94 months;The tumor free survival rateand of the LR group at 12,24 and 36 months after surgery was 66.4%、42.1%、29.3% and the median tumor-free survival time of the LR group was 23.52 months.The difference was statistically significant(P<0.05).7.There was no significant difference between the two groups in the amount of intraoperative blood transfusion(4 VS 10)、serum indexes of liver function(AST、ALT、TBil、PT、ALB)in the first and four day after operation and in the length of days in hospital(P<0.05).Conclusion:Radiofrequency ablation assisted liver resection for hepatocellular carcinoma has high safety,low incidence of complications and the median tumor-free survival time is longer.But the hospitalization expenses was higher. |
