The Research Of TCM Syndrome Element Study The Symptoms And Signs Of DKD Stage ? ? And Relationship With Clinic

Objective:Based on 98 cases of patients with diabetic nephropathy(? period,? period)of traditional Chinese medicine(TCM)clinical data and statistical analysis of four diagnostic information,study the clinical features of diabetic nephropathy and the TCM syndrome distribution regularity,to explore the risk factors of the disease,provide reference for TCM syndrome differentiation and treatment.Methods:In accordance with the unified set of questionnaire study of patients included in the standard,collecting the clinical data of patients with diabetic nephropathy,TCM four diagnostic information,using "syndrome factor differentiation to learn" in the"scale" syndrome differentiation element to obtain evidence,using descriptive statistical analysis and other methods,to explore the clinical characteristic,summarized the distribution characteristics of the syndromes.Result:1.In this study,? period,IV period of disease syndrome has a reputation for kidney primarily,involves the spleen and liver lung and stomach;Most for multiple syndrome factor combination,? phase of the disease a card has a reputation for spleen and kidney is given priority to,? period is given priority to with with liver and spleen kidney disease.2.The frequencies of disease sexual syndrome elements is shown below ?followed by wet(83.87%)>Yin qi deficiency(74.19%)>(72.58%)>phlegm(46.77%)(46.77%)>=heat and qi stagnation(29.03%)=blood deficiency(29.03%)=Yang deficiency(29.03%)>blood stasis(8.06%)>blood heat(1.62%);Stage IV was followed by wet(83.33%)=qi deficiency(83.33%)=Yin deficiency(83.33%)>sputum(63.89%)>heat(52.78%)>blood deficiency(47.22%)>Yang deficiency(33.33%)>qi stagnation(25.00%)=blood stasis(25.00%).3.According to the classification of deficiency and reality,the combination of deficiency and syndrome includes Yin deficiency,qi deficiency,qi Yin deficiency,qi Yang deficiency,qi deficiency,blood deficiency,Yin deficiency,qi deficiency,Yin deficiency and Yang deficiency.Above two deficiencies in stage IV(accounted for 72.22%)are much more than that in stage ?(accounted for 69.36%).The empirical combination is more complex,the syndrome names ranked by frequency of occurrence:phlegm-dampness syndrome(27.42%)>dampness-heat syndrome(25.81%)>dampness-heat syndrome(11.29%)>blood fever syndrome(1.61)=phlegm-dampness-stasis syndrome(1.61%);? phase frequency of the evidence of phlegm dampness syndromes(27.78%)>blood stasis phlegm dampness syndrome(25.00%)>wet and heat syndrome(22.22%)>wet aggregates(8.33%).4.The prevalence of diabetic nephropathy was higher in men than in women(1.5:1).The average age was 61.74±8.86 years,and the peak age was 61-70 years,accounting for 45.9%.The mean course of diabetes was 11.74±6.18 years.Overweight and obese patients were more,accounting for 62.3%.5.There was no statistically significant difference in the mean age and course of disease of stage ? and ? patients(P>0.05).? period in patients with BMI significantly longer than ? period(P<0.05).6.1n this study,patients with hypertension accounted for 72.45%,those with dyslipidemia accounted for 94.90%,those with hyperuricemia accounted for 28.57%,those with cerebral infarction accounted for 22.45%,and those with coronary heart disease accounted for 35.71%.? patients compared with IV period patients:diabetes mellitus retinopathy(43.5%/72.7%),the proportion of cerebral infarction(12.9%/38.9%)increased significantly(P<0.05),hypertension(67.7%/80.6%),and the combining both coronary heart disease(29.0%/47.2%),combined dyslipidemia disease(95.2%/94.4%),merging,the proportion of high uric acid hematic disease(22.7%/38.9%),no statistical sign.ificance(P>0.05).7.BUN,Cr and TG of stage IV patients were significantly higher than that of stage ? patients(P<0.05).There was no statistical significance in FBG,HDL-C,LDL-C,UA and HbA1c(P>0.05).Conclusion:1.Stage ?,? disease in patients with kidney is given priority to,a card has a reputation for involving the spleen and liver,lung and stomach,etc.,with many viscera disease more ? period is given priority to with spleen and kidney disease,?period mainly with liver and spleen kidney disease;The pathogenesis is deficiency and solid inclusion,and the syndrome elements of the disease are mainly qi and Yin deficiency,involving deficiency of Yang and blood,as well as dampness,phlegm,heat,qi stagnation,blood heat and blood stasis.Including ? period Yin deficiency of heavy gas,with the development of the illness to IV period,qi deficiency,blood deficiency,Yin deficiency and Yang deficiency is aggravating,blood stasis and phlegm wet.2.Risk factors for DKD may be related to gender(male).age.overweight and obesity.3.The occurrence/development of DKD and is closely related to the duration of diabetes,? period patients average duration than ? period.4.With the development of DKD,the incidence of diabetic retinopathy,cardiovascular,cerebrovascular and metabolic diseases(hypertension,dyslipidemia,hyperuricemia,cerebral infarction,coronary heart disease)increased significantly.?phase of patients with diabetic retinopathy,cerebral infarction,high blood pressure,coronary heart disease,high blood uric acid significantly higher than the proportion of? period patients,? period in patients with no obvious difference was found between patients with hyperlipidemia and IV period.5.? period the patient's BUN,Cr,TG,HDL-C,LDL-C,UA,HbA1c values were higher than ? period patients,FBG in patients with stage ?,? has no obvious difference.