Epidemiology Of Hypertension Among The Plains Chinese Han Nationality Who Working At The Very High Altitude

Objective:Altitude is one of the influencing factors of hypertension.The very high altitude regions(altitude of 3500-5500m)have some impact of people due to its special natural geographical environment.At present,data on epidemiological surveys of hypertension in the very high altitude regions at China or abroad are scarce.Most of the survey respondents are local residents,and there is almost no study on the plains population.Therefore,the present study is represented by the Seni District(altitude of 4507m)in Naqu city of Tibet.The epidemiology research of hypertension among the plains Chinese Han who working at the Seni District to determine the prevalence of hypertension and related risk factors in this population.Methods:This was a cross-sectional survey that began in June 2017 and ended in May 2018.The study population is Chinese adult Han(?18 years old)who come from low altitude Regions(altitude<200m).The inclusion criteria were residing in Seni District(altitude of 4507m),Naqu city of Tibet,over 2 years(excluding 2-3 months of vacation)at least before interview.Through height,weight,blood pressure,Sa O2 measurement and fill in the questionnaires information collection,including gender,age,marital status,education level,occupation,PSQI scale,smoking status,drinking status,years of work years in local and personal history of hypertension.Relevant indicators are stratified,the age is divided into four groups: 18-29,30-39,40-49,and ?50 years;the education level is divided into four groups: primary school the following,primary school,middle school,and university and above;divided by PSQI scores with or without sleep disorder;divided into three groups according to BMI: normal,overweight and obesity.Through statistical description of the data,univariate analysis and binary logistic regression analysis,the prevalence of hypertension and related risk factors in the plains Chinese Han nationality who working at the very high altitude wereobtained.Results:A total of 1,241 participants were enrolled,including 772 males and 469 females.1.The total crude prevalence of hypertension was 33.9%,Male incidence of hypertension is significantly higher than female one,has statistical significant(45.9%vs 14.3%,P<0.001).2.The prevalence of hypertension among four age groups were 21.13%,25.07%,41.61% and 52.06%,respectively.Prevalence of male is higher than that of female in all age groups(31.74% vs 3.06,41.71% vs 8.15%,49.25% vs 27.27%,60.67% vs22.73%).Except for women ?50 years of age group,the prevalence of hypertension increases with age.The prevalence of hypertension between male and female in the same age group was statistically significant(P <0.001).3.The systolic blood pressure in the four age groups were 116.18 ± 18.94 mm Hg,123.21 ± 20.95 mm Hg,129.75 ± 23.24 mm Hg,and 135.84 ± 27.55 mm Hg,respectively.The diastolic pressures were 76.26±13.82 mm Hg,80.91±14.69 mm Hg,85.51±16.78 mm Hg and 87.11±18.04 mm Hg,respectively.Blood pressure levels increase with age,both systolic and diastolic blood pressure were higher in male than female in the same age group.Except for the systolic blood pressure in the 40-49 age group,it was statistically significant(P <0.05).4.Between the hypertension and non-hypertension groups,the differences of the hypertension prevalence among gender,age,smoking,marital status,education level,sleep status,smoking,alcohol,Sa O2 and work of years were statistically significant(P<0.001).There was no significant difference in the prevalence of hypertension among different occupations and BMI(P>0.05).5.Between the male and female groups,the differences in age,marital status,education level,occupation,sleep status,smoking,alcohol,Sa O2 and work of years were statistically significant(P <0.05).There was no significant difference in BMI(P>0.05).6.Binary logistic regression showed that male(OR 5.08,95%CI 3.78-6.82,P<0.001),age(OR 1.06,95% CI 1.05-1.08,P<0.001),sleep disorder(OR 5.62,95% CI4.22-7.48,P<0.001),smoking(OR 2.86,95% CI 2.16-3.77,P<0.001),alcohol(OR3.08,95% CI 2.40-3.94,P<0.001),Sa O2(OR 0.82,95% CI 0.80-0.85,P<0.001),workyears(OR 1.06,95% CI 1.04-1.08,P<0.001)were risk factors for research population hypertension.Conclusion:The plains Chinese Han nationality who working at the very high altitude is extremely susceptible to hypertension.Male,increasing age,sleep disorder,smoking,alcohol,decreased Sa O2,and increased work years in local are important risk factors for hypertension.