Effects Of Huangdi Nei Zhen On Inflammatory Factors And Clinical Prognosis In Patients With Qi Deficiency And Blood Stasis Syndrome After PCI For Coronary Heart Disease

Objective:To observe the effect of Huangdi Nei Zhen on inflammatory factors and clinical prognosis in patients with Qi deficiency andblood st asis syndrome after PCI for coronary heart disease.Methods:From November 2018 to November 2019,60 patients with qi-deficiency and blood-stasis after PCI were selected from the second section of the department of cardiology,the first affiliated hospital of guangxi university of traditional Chinese medicine.60 cases were divided intocontrol group and treatment group by random number table method.Thecontrol group was treated with conventional western drug.The treatmentgroup was treated with Huangdi Nei Zhen on the basis of the control group.The treatment principle refers to the four principles of "treatmentof upper diseases and lower diseases,treatment of left diseases and right diseases,seeking for the same Qi,and seeking for the exchange of yin and Yang".According to the principle of "six,three,two and one",the acupuncture time is 45 minutes per time,and the acupuncture time is five times a week for one month.The changes of TCM symptom score,quality of life scale score,serum hs-CRP and IL-6 levels before and after treatment were observed.Blood Lipid levels and ECG were compared before and 3 months after treatment,and the incidence of adverse cardiac events(MACE)was followed up.Results: 1.The results of TCM syndrome score:before and after treatment,thetotal score of TCM syndrome in the two groups was lower than before,the difference was statistically significant(P<0.05);after treatment,the total score of TCM syndrome in the treatment group was lower than that in the control group,the difference was statistically significant(P<0.05).2.Results of serum hs-CRP and IL-6 levels:After treatment,the levels of hs-CRP and IL-6 in the two groups were lower than before(P<0.05);After treatment,the levels of hs-CRP and IL-6 in the treatment group decreased more significantly(P<0.05).3.Results of clinical efficacy of traditional Chinese medicine:The overall effective rate of the treatment group was 93.3%,and that of the control group was 76.6%.The overall effective rate of the treatment group was higher than that of the control group,the difference was statistically significant(P<0.05).4.Quality of life score results:Before and after treatment,the patients in the two groups improved in seven aspects: physiological function,physical pain,overall health,energy,social function,mental health and health changes(P<0.05);After treatment,the therapeutic effect of the treatment group was better than that of the control group in five aspects:physiological function,physical pain,overall health,energy and health changes(P<0.05).5.ECG results:Three months later,the ECG was reexamined,the overall effective rate of the treatment group was 86.6%,and the overall effective rate of the control group was 56.6%.The ECG effect of the treatment group was better than that of the control group,with statistical difference(P<0.05).6.Results of blood lipid level:The levels of TC,TG and LDL-C in the two groups were lower than those before treatment(P<0.05).The levels of TC and TG in the treatment group were significantly lower than those in the control group(P<0.05).7.Results of MACE incidence after 3 months:After 3months of follow-up,the total incidence of adverse cardiac events was 6.6%in the treatment group and 16.6% in the control group,with no significant difference between the two groups(P>0.05).Conclusion:1.Huangdi Nei Zhen can improve the clinical symptoms of qi-deficiency and blood-stasis patients with coronary heart disease after PCI,and it also has the function of anti-inflammatory and lowering blood lipid,with fewer adverse reactions,which has positive significance for improving the quality of life of qi-deficiency and blood-stasis patients with coronary heart disease after PCI.