| Objective: To observe the clinical effect and safety of Paishit ang No.? in the perioperative period of upper ureteral calcul i with scorching damp heat and stasis type under SWL treatment,and provide basis for optimizing the treatment plan of integra ted traditional Chinese and western medicine for urinary tract stones.Methods:A prospective study was conducted on 92 patients admitted to the urology department of Huayuanshan District,Hubei Provincial Hospital of Traditional Chinese Medicine from January 2018 to December 2019.They were divided into group A(simple in vitro lithotripsy group)and B using random number table method.Group(for oral administration of Paishitang Recipe III after crushing in vitro for 1 week),Group C(for oral administration of Paishitang Recipe III for 10 days before crushing in vitro,and oral administration of Paishitang Recipe III for 1 week after crushing),three groups All were given general treatment(including instructing each patient to drink 2000 ml of water every day,exercising and tapping the stone area by themselves to assist stonedischarge),and recording the net rate of stone discharge and stones in the three groups of cases at 1 week,2 weeks,and 4 weeks after lithotripsy The unremoved rate,stone discharge time and discharge time,VAS score,main clinical symptoms and signs score,incidence of hematuria,positive rate of urinary leukocytes,adverse reactions and other related indicators were analyzed and processed by SPSS23.0.Results:1.The net rate of stone discharge:when after 1 week,2 weeks,4 weeks after SWL,The three groups were group A(10.71%,21.43%,28.57%),group B(20.00%,30.00%,60.00%),group C(50.00%,62.50%,71.88%).2.Net rate of unexcluded stones: When after 1 week,2 weeks,and 4 weeks after SWL,Group A(25.0%,32.1%,57.1%),Group B(56.7%,53.3%,26.7%),Group C(28.1%,25.0%,21.9%).3.The time of stone discharge: The three groups are group A(10.33 ± 5.39)d,group B(6.73 ± 4.65)d,and group C(4.28± 4.01)d.4.Removal time: The three groups are group A(12.88 ±6.01)d,group B(12.44 ± 5.53)d,and group C(8.26 ± 4.21)d.5.VAS score: When 1 week,2 weeks,and 4 weeks after SWL the three groups of SWL are divided into group A(4.32 ± 2.84,3.75± 2.62,3.25 ± 2.17)and group B(3.33 ± 2.57,3.00 ± 2.26,2.33 ± 1.95),Group C(2.62 ± 2.15,2.28 ± 1.80,1.97 ± 1.61)points.6.The incidence of hematuria: When 3 days,1 week,2 weeks,and 4 weeks after SWL three groups of SWL are group A(96.4,92.9,85.7,64.3)and group B(93.3%,90.0%,76.7%,63.3%),Group C(93.8%,81.3%,68.8%,31.2%).7.Positive rate of urinary leukocytes: When 3 days,1week,2 weeks,and 4 weeks after SWL the three groups of SWL were group A(96.4%,92.9%,96.4%,64.3%),group B(93.3%,93.3%,93.3 %,66.7%),Group C(93.8%,93.8%,84.4%,28.1%).8.Symptoms and signs: When 1 week,2 weeks,and 4 weeks after SWL the three groups were divided into group A(10.75 ±2.85,6.50 ± 2.60,3.36 ± 1.81),group B(9.33 ± 2.07,5.90 ±2.28,2.83± 1.21)points,Group C(8.03 ± 2.21,6.34 ± 2.02,2.63 ± 1.24)points.9.Adverse reaction rate: The three groups of adverse reaction rates were group A(7.14%),group B(6.67%),and group C(10%).Conclusion:1.Net discharge rate of stones: 1 week and 2 weeks after SWL,group C was significantly better than groups A and B(P<O.05).SWL was combined with Paishitang No.? during perioperative period,especially before surgery The use of medicine can significantly increase the net rate of stone discharge.2.Net rate of undischarged stones: Group B was superior to Group A at 1 week after SWL(P < O.05),and there was no significant difference between the three groups at 2 weeks after SWL(P>0.05),and at 4 weeks after SWL,Group C was lower than group A(P < O.05),and SWL perioperative period was combined with Paishitang No.? to promote stone removal.3.The time of stone discharge and the time of net discharge: Group C is significantly better than Group A and Group B(P<O.05).SWL perioperative period is combined with Paishitang No.?,especially the preoperative medication can be significantly shortened Course of illness.4.VAS score: Group C was lower than Group A,the difference was statistically significant(P < O.05),and SWL perioperative period combined with Paishitang No.? treatment can significantly relieve pain and improve symptoms.5.Incidence of hematuria and positive rate of urinary leukocytes: Group C is better than Group A and Group B(P<O.05).SWL is combined with Paishitang No.? during perioperative period,especially before surgery,at 4 weeks The incidence of hematuria and the positive rate of urinary leukocytes were significantly reduced.6.Symptoms and signs score: 1 week after SWL,group C was better than groups A and B(P<0.05),there was no significant difference between the three groups at 2 weeks and 4 weeks after SWL(P > 0.05).SWL combined with Paishitang No.? in the perioperative period,especially the preoperative medication,had the best effect in relieving the patient's overall symptoms at 1week.7.The adverse reaction rate of the three groups was not statistically significant(P>0.05),and Paishitang No.? had no obvious toxic and side effects.In summary,the combined application of Paishitang No.?during the perioperative period of upper ureteral calculi of lower scorching dampness and heat and stasis type by SWL,especially preoperative medication,can significantly increase the net rate of stone discharge,reduce the time of stone discharge,reduce patient pain,and improve Related clinical symptoms,no obvious adverse reactions,worthy of further research. |
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