Clinical Observation On Intervention Of Carotid Atherosclerotic Plaque And Phlegm-Stagnation Syndrome With Traditional Chinese Medicine And TCM Movement

Objective: In this study,traditional Chinese medicine and TCM movement were intervened to the patients with carotid atherosclerotic plaque and phlegm-stagnation syndrome.in order to evaluate the clinical efficacy and safety of Sanjietongmai prescription combined with Baduanjin health function,the changes of patients' blood lipid routine,carotid ultrasound,TCM syndrome scores,blood routines,and urine routines before and after treatment were clinically observed.this can provide a theoretical basis for the treatment of carotid atherosclerotic plaques.Methods: The cases originated from the outpatient and inpatient department of the affiliated hospital of Changchun University of Chinese Medicine.The consultation time was between December 2018 and May 2019,and the patients were between 18 and 80 years old.A total of 72 patients with carotid atherosclerotic plaque and phlegm-stagnation syndrome were included.They were randomly divided into a control group and a test group,with 36 patients in each group.The control group was given aspirin enteric-coated tablets combined with atorvastatin calcium tablets.Based on the control group,the test group was given the synergistic treatment of Sanjietongmai prescription combined with Baduanjin health function,and the treatment course was 12 weeks.The course of treatment was 12 weeks.Regularly observe and record blood lipids(TC,TG,LDL-C,HDL-C),carotid color Doppler ultrasound(carotid IMT,carotid Crouse plaque score),TCM syndrome scores,TCM syndrome efficacy,blood routines,and urine routines Changes,the data collected during the test was analyzed by using SPSS 22.0.Results: In this study,72 patients were included,3 patients were excluded or shed during the test,and 69 patients were finally completed.After treatment in the control group and the test group,the medical syndrome score,TC,TG,LDL-C,and carotid Crouse plaque score were all improved,and the test group was better than the control group(P < 0.05).In addition,carotid IMT and HDL-C also improved,but there was no statistical difference between the test group and the control group(P> 0.05).The total effective rates of the test group and the control group were 85.29% and 74.29%,respectively.After the rank-sum test in the two groups,P < 0.05,the test group was better than the control group.In terms of safety,there were no significant abnormalities in safety indicators such as urine routine,blood routine,and liver and kidney function before and after treatment in the two groups of patients.Conclusion: Sanjietongmai prescription combined with Baduanjin health function can further improve the clinical symptoms of TCM,carotid IMT,carotid Crouse plaque score,blood lipid levels,and hematuria in patients with carotid atherosclerosis,liver and kidney function and other safety indicators were not significantly abnormal.This shows that the Sanjietongmai prescription combined with Baduanjin health function has a good clinical effect,can also delay the progression of carotid atherosclerotic lesions,and has good safety.