Clinical Study Of Tiao Shen Ping Kang Prescription Treating Insomnia With Overflow Pulse

Objective: To observe and compare the clinical efficacy and safety of Tiaoshen Pingkang Decoction and Alprazolam Tablets in treating insomnia with overflowing pulse,and to provide Tiaoshen Pingkang Decoction for treating insomnia(overflowing pulse syndrome).Validity basis,and preliminary theoretical discussion and research on it.Methods: Cases were selected from 80 patients who met the inclusion criteria in the Department of Brain Diseases of the Affiliated Hospital of Shanxi University of Traditional Chinese Medicine from January 2019 to October 2019.Random and parallel control methods were adopted to randomize the subjects.They were divided into a treatment group(Tiaoshen Pingkang Decoction)and a control group(Alprazolam tablets)of 40 cases,with a course of treatment of 4 weeks.The treatment effect was evaluated by calculating the Pittsburgh Sleep Index Scale(PSQI)scores before and after treatment,the SPIEGEL scale score changes before and after treatment,and the TCM Symptoms Scale score before and after treatment.Results: 1.Evaluation of curative effect indicators: There was no significant difference between the two groups before treatment with HAMA score,PSQI score,SPIEGEL scale score and TCM symptom scale score(P> 0.05),indicating that the two groups of subjects can be clinically compared Observation;after treatment,Tiaoshenpingkangtang group and alprazolam group can significantly reduce PSQI score,SPIEGEL scale score and TCM symptom scale score,the difference is statistically significant(P <0.05),Both Tiaoshenpingkang decoction and alprazolam tablets can improve the symptoms of overflow vein insomnia;the difference between the two groups in reducing the TCM symptom score after treatment is statistically significant(P <0.05),the total effective rate of the treatment group 92.31%,the total effective rate of the control group was 74.36%,indicating that Tiaoshen Pingkang Decoction is superior to alprazolam in improving TCM symptoms.2.Safety judgment: During the course of the study,the treatment group found that 1 patient had diarrhea discomfort after taking the drug for one week.Considering that it was related to rhubarb in the prescription,the dosage of rhubarb was reduced to 5 grams and the rest of the drugs continued to be taken.The discomfort symptoms disappeared and continued to be included in the treatment.There were no significant differences between the treatment group and the control group before and after safety evaluation.(P> 0.05).Conclusion: Tiaoshen Pingkang Decoction and Alprazolam Tablets are both safe and effective;Tiaoshen Pingkang Decoction has a significant effect in improving patients with insomnia and accompanying symptoms,and it is worthy of further clinical use.