Correlation Study On Relationship Between Different Syndrome Types Of Uyghur Medicine And 24hABPM,Physical And Chemical Indexes In Essential Hypertension

Objective: Analyze the 24 h ABPM results,blood lipids,AI,AIP,AASI,Hcy,Cys-C change rules and correlation on different Uyghur medicine syndrome types of EH,and provide scientific and objective evidence for clinical treatment of EH in Uyghur medicine.Methods: A total of 334 patients who were diagnosed with primary hypertension at the Uyghur Medical Hospital of Xinjiang Uygur Autonomous Region from September 2018 to November 2019 were selected.Uyghur medicine syndrome types was identificated.each group of patients records general information,The results of 24 h ABPM,lipid,AI,AIP,AASI,Hcy and Cys-C were collected,and each data was statistically analyzed.Results: 1.In this study,the gender of EH patients was significantly different in the main Uyghur medicine syndrome types(P<0.05)The distribution of male patients in the abnormal balgham type was the most significant type;the age of patients in the four main Uyghur medicine syndrome types were was significantly different(P<0.05)the elder patients were significant in abnormal balgham,The age distribution of the elderly,60-70 years old patients are more common;The distribution of classification and risk stratification of hypertension patients in tertiary hypertension with high risk group were significant;There was a significant difference in the classification of hypertension among the three syndrome subtypes of Uyghur medicine(P < 0.05).tertiary hypertension were astringent balgham type was significant;In temperament distribution,the patients with damp cold temperament were the most.The frequency of the main Uyghur medicine syndrome types of EH patients is abnormal balgham > abnormal sepra> abnormal sawda> abnormal khan,and the frequency of subtypes is astringent balgham> salty balgham > leek color sepra> bule sepra>flavescens sepra> thickened khan>brunt sawda.2.The blood type of EH patients was significantly different between the main syndrome types(P < 0.05),and the difference between the subtypes was statistically significant(P < 0.05).In the main types,B blood type was significant in astringent balgham.when comparing laboratory parameters of HDL-C,Hcy,and Cys-C differences among the main Uyghur medicine syndrome types were statistically significant(P<0.05).HDL-C levels of abnormal balgham types in the main Uyghur medicine syndrome types were significantly lower.Hcy levels are significantly higher,Cys-C levels of abnormal khan are significantly higher,and among subtypes,Hcy levels are significantly higher than those of other syndrome types of astringent balgham type.3.The AIP level of arteriosclerosis index in EH patients was statistically significantbetween the main Uyghur medicine syndrome types and subtypes(P <0.05).The AIP levels of abnormal balgham types in the main Uyghur medicine syndrome types were significantly higher,and AI and AIP were statistically significant among the subtypes(P<0.05).The salty balgham type AI and AIP levels in the subtypes were significantly higher.4.The results of 24 h ABPM in EH patients were significantly different from those in the main types(P < 0.05),The average systolic blood pressure level of abnormal khan type was significantly lower than that of other types in the daytime,and the difference of pulse pressure between the main types were statistically significant(P < 0.05).The difference of pulse pressure of abnormal khan type was significantly lower than that of other types.The difference of SBP,DBP peak value and the lowest value of 24 h ABPM between EH patients and different types was statistically significant(P < 0.05)The distribution of astringent balgham at night(19:00-23:00)was the most significant,the difference between the main types in the lowest DBP time period of the whole day were statistically significant(P < 0.05),and the distribution of abnormal balgham at afternoon(13:00-17:00)was significant.There was a significant difference between the subtypes of Uighur medical syndrome in the lowest SBP time of the whole day(P < 0.05)The distribution of astringent balgham type was significant in the afternoon(13:00-17:00).5.There was correlation between abnormal balgham and HDL-C,Hcy,AIP,pulse pressure difference in daytime and systolic pressure standard difference at night(P < 0.05).Among them,HDL-C was negatively correlated with AIP,the rest was positively correlated with AIP(P< 0.05);There was a positive correlation between astringent balgham and TG,Hcy,night systolic blood pressure(P < 0.05);There was a positive correlation between salty balgham and Hcy,AI,AIP(P < 0.05);There was a positive correlation between theleek color sepra and AIP,the whole day pulse pressure difference(P < 0.05);6.6.Hcy level was correlated with abnormal balgham of EH(P < 0.05).Conclusion: 1.The main Uyghur medicine syndrome types is abnormal balgham,main subtype are astringent balgham,salty balgham and leek color sepra of EH,and it is more common in elderly and male patients with abnormal balgham.2.Blood type,HDL-C,Hcy,Cys-C,AI,AIP,TG,mean blood pressure,standard deviation of blood pressure and pulse pressure difference have certain differences among various Uyghur medicine syndrome types,which can be used as a reference index for Uyghur medicine syndrome differentiation and treatment;3.The risk of hypertension in astringent balgham type of EH was more likely to occur at night(19:00-23:00).The incidence of hypertension crisis in the afternoon(13:00-17:00)of abnormal and astringent balgham type of EH was lower.4.The risk of abnormal balgham type of EH increased with the increase of Hcy level.